Basic information Safety Supplier Related

E3 ligase Ligand-Linker Conjugates 14

Basic information Safety Supplier Related

E3 ligase Ligand-Linker Conjugates 14 Basic information

Product Name:
E3 ligase Ligand-Linker Conjugates 14
Synonyms:
  • E3 ligase Ligand-Linker Conjugates 14
  • E3 ligase Ligand-Linker Conjugates 14 (TFA)
  • Cereblon Ligand-Linker Conjugates 3 (TFA)
  • Pomalidomide Related Compound 5 Triflate
  • E3 Ligase Ligand-Linker Conjugates,Cereblon Ligand-Linker Conjugates 3,Thalidomide O amido PEG3 C2 NH2 TFA,Thalidomide-O-amido-PEG-3-C2-NH2 TFA,E3 ligase Ligand-Linker Conjugates 14,inhibit,Inhibitor,ThalidomideOamidoPEG3C2NH2 TFA
CAS:
1957236-21-3
MF:
C25H31F3N4O11
MW:
620.54
Mol File:
1957236-21-3.mol
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E3 ligase Ligand-Linker Conjugates 14 Chemical Properties

storage temp. 
2-8°C, sealed storage, away from moisture
form 
Solid
color 
White to off-white
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E3 ligase Ligand-Linker Conjugates 14 Usage And Synthesis

Uses

Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

IC 50

Cereblon

References

[1] BRADNER, James, et al. METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL MOLECULES. WO2017024317A2.

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