E3 Ligase Ligand-Linker Conjugates 19 Chemical Properties

Boiling point:

757.5±60.0 °C(Predicted)

Density 

1.397±0.06 g/cm3(Predicted)

solubility 

DMF: insol; DMSO: insol; Ethanol: insol; PBS (pH 7.2): 3 mg/ml

form 

A solid

pka

10.68±0.40(Predicted)

E3 Ligase Ligand-Linker Conjugates 19 Usage And Synthesis

Description

Thalidomide-O-acetamido-C4-amine HCl salt is comprised of a Thalidomide based cereblon ligand and a ligand-linker conjugate. This E3 ligase ligand-linker conjugate is used in PROTAC technology.

E3 Ligase Ligand-Linker Conjugates 19(1799711-24-2)Related Product Information

• E3 Ligase Ligand-Linker Conjugates 22
• E3 ligase Ligand-Linker Conjugates 11
• 1H-Isoindole-1,3(2H)-dione, 4-[2-(2-aminoethoxy)ethoxy]-2-(2,6-dioxo-3-piperidinyl)-
• Cereblon Ligand 1
• E3 Ligase Ligand-Linker Conjugates 21
• Thalidomide-O-PEG4-Propargyl
• Thalidomide-linker 10
• Acetamide, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl-
• Thalidomide-O-amido-C4-NH2 hydrochloride
• Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
• Thalidomide-O-amido-C8-NH2 hydrochloride
• Thalidomide-O-PEG4-Boc
• tert-butyl 3,3'-(2-aMino-2-((3-tert-butoxy-3-oxopropoxy)Methyl)propane-1,3-diyl)bis(oxy)dipropanoate
• Thalidomide-linker 13
• E3 Ligase Ligand-Linker Conjugates 20
• N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide TFA salt
• E3 ligase Ligand-Linker Conjugates 17
• E3 Ligase Ligand-Linker Conjugates 1