Basic information Description Safety Supplier Related
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D-(-)-Salicin

Basic information Description Safety Supplier Related

D-(-)-Salicin Basic information

Product Name:
D-(-)-Salicin
Synonyms:
  • D-(-)-SALICIN
  • D-SALICIN
  • 2-(HYDROXYMETHYL)PHENYL-BETA-D-GLUCOPYRANOSIDE
  • 2-(HYDROXYMETHYL)PHENYL-BETA-D-GLUCOPYYRANOSIDE
  • 2-(HYDROXYMETHYL)PHENYL-BETA-D-GLUCOSIDE
  • 2-(Hydroxymethyl)phenyl hexopyranoside
  • SALICYLALDEHYDE-B-D-GLUCOSIDE
  • SALICYLALCOHOL BETA-D-GLUCOSIDE
CAS:
138-52-3
MF:
C13H18O7
MW:
286.28
EINECS:
205-331-6
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Plant extract
  • Herbs & Natural Remedies
  • Sugars, Carbohydrates & Glucosides
  • Biochemistry
  • Glucose
  • Glycosides
  • Sugars
  • Natural Plant Extract
  • HISMANAL
  • carbohydrate
  • Inhibitors
Mol File:
138-52-3.mol
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D-(-)-Salicin Chemical Properties

Melting point:
196-202 °C
alpha 
-61.5 º (c=5, water)
Boiling point:
388.65°C (rough estimate)
Density 
1.4340
refractive index 
-62 ° (C=3, H2O)
storage temp. 
Store at RT.
solubility 
36g/l
pka
12.80±0.70(Predicted)
form 
Fine Crystalline Powder
color 
White
Water Solubility 
36 g/L (15 ºC), 250 g/L (60 ºC)
Merck 
14,8324
BRN 
89593
Stability:
Stability Stable, but light sensitive. Incompatible with strong oxidizing agents.
InChIKey
NGFMICBWJRZIBI-MICYEWLZSA-N
CAS DataBase Reference
138-52-3(CAS DataBase Reference)
NIST Chemistry Reference
Salicin(138-52-3)
EPA Substance Registry System
.beta.-D-Glucopyranoside, 2-(hydroxymethyl)phenyl (138-52-3)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
43
Safety Statements 
36/37-37-24/25-36
WGK Germany 
3
RTECS 
LZ5901700
3-10
TSCA 
Yes
HS Code 
29389090

MSDS

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D-(-)-Salicin Usage And Synthesis

Description

D(-)-Salicin is a traditional medicine which has been known to exhibit anti-inflammation and other therapeutic activities, it can inhibit the LPS-induced inflammation in RAW264.7 cells and mouse models.

Chemical Properties

white crystals or powder

Uses

analgesic, antipyretic

Uses

H1 antihistamine (nonsedating)

Uses

Standard substrate in evaluating enzyme Preparations contg b-glucosidase: Weidenhagen, Z. Ver. Zucker-Ind. 79, 591 (1929).

Definition

ChEBI: An aryl beta-D-glucoside that is the beta-D-glucoside of the phenolic hydroxy group of salicyl alcohol.

Purification Methods

Crystallise D(-)-salicin from EtOAc, EtOH or water and sublime it at 190-195o/12mm. [Armour et al. J Chem Soc 412 1961, IR: Pearl & Darling J Org Chem 24 731 1959, Beilstein 17 III/IV 2986, 17/7 V 113.]

D-(-)-SalicinSupplier

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