1-METHOXY-4-NITRONAPHTHALENE
1-METHOXY-4-NITRONAPHTHALENE Basic information
- Product Name:
- 1-METHOXY-4-NITRONAPHTHALENE
- Synonyms:
-
- 1-METHOXY-4-NITRONAPHTHALENE
- 4-Methoxy-1-nitronaphthalene
- 1-Methoxy-4-nitronaphthalene,99%
- 1-Methoxy-4-nitronaphthalene 99%
- 1-Methoxy-4-nitronaphthalin
- 1-Nitro-4-methoxynaphthalene
- methyl4-nitronaphthylether
- Naphthalene,1-methoxy-4-nitro-
- CAS:
- 4900-63-4
- MF:
- C11H9NO3
- MW:
- 203.19
- EINECS:
- 225-528-0
- Product Categories:
-
- Naphthalene derivatives
- Nitro Compounds
- Nitrogen Compounds
- Organic Building Blocks
- Mol File:
- 4900-63-4.mol
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1-METHOXY-4-NITRONAPHTHALENE Chemical Properties
- Melting point:
- 83-85 °C (lit.)
- Boiling point:
- 341.49°C (rough estimate)
- Density
- 1.2621 (rough estimate)
- refractive index
- 1.4950 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
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MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
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1-METHOXY-4-NITRONAPHTHALENE Usage And Synthesis
Chemical Properties
yellow to orange crystalline powder
Uses
1-Methoxy-4-nitronaphthalene is used as a reagent in the synthesis of UMI-77 (U700850); a small molecule inhibitor of Mcl-1 which blocks and attenuates pancreatic cell cancer growth. Also an anticancer agent.
Synthesis Reference(s)
Synthesis, p. 70, 1985 DOI: 10.1055/s-1985-31110
Purification Methods
Purify it by chromatography on silica gel, then recrystallise it from MeOH or EtOH (yellow needles). [Hodgson & Habeshaw J Chem Soc 47 1942, Bunce et al. J Org Chem 52 4214 1987, Beilstein 6 H 616, 6 III 2938.]
1-METHOXY-4-NITRONAPHTHALENESupplier
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1-METHOXY-4-NITRONAPHTHALENE(4900-63-4)Related Product Information
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