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3-Aminopropylphosphonic acid

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3-Aminopropylphosphonic acid Basic information

Product Name:
3-Aminopropylphosphonic acid
Synonyms:
  • 3-AMINOPROPYLPHOSPHONIC ACID
  • TIMTEC-BB SBB004184
  • aminopropylphosphonate
  • 3-AMINOPROPYLPHOSPHONIC ACID 97%
  • 3-AMinopropylphosphonic
  • 3-aminopropanephosphonic acid
  • 3-Aminopropyl-phosphonate
  • NSC-133832
CAS:
13138-33-5
MF:
C3H10NO3P
MW:
139.09
Product Categories:
  • AgonistsOrganic Building Blocks
  • GABAergics
  • API intermediates
  • Phosphonic/Phosphinic Acids
  • Phosphorus Compounds
  • Neurotransmitters
Mol File:
13138-33-5.mol
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3-Aminopropylphosphonic acid Chemical Properties

Melting point:
294 °C (dec.)(lit.)
Boiling point:
343.0±44.0 °C(Predicted)
Density 
1.378±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMF: 5 mg/ml; DMSO: 2 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
pka
2.11±0.10(Predicted)
form 
Powder
color 
Off-white to faintly greenish
Water Solubility 
soluble
InChIKey
GSZQTIFGANBTNF-UHFFFAOYSA-N
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29310099

MSDS

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3-Aminopropylphosphonic acid Usage And Synthesis

Chemical Properties

Off-white to faintly greenish powder

Uses

3-Aminopropylphosphonic acid was used as a selective antagonist of GABA(C) receptor.

Definition

ChEBI: (3-aminopropyl)phosphonic acid is a phosphonic acid in which the hydrogen attached to the phosphorus of phosphonic acid is substituted by a 3-aminopropyl group. It is a partial agonist of GABAB receptors. It has a role as a GABAB receptor agonist. It is a primary amino compound and a member of phosphonic acids. It is functionally related to a phosphonic acid. It is a tautomer of a (3-aminopropyl)phosphonic acid zwitterion.

General Description

The relative nonspecific binding of the DNA-conjugated gold nanoparticles (AuNPs) to the indium-tin oxide electrodes modified with 3-aminopropylphosphonic acid was examined by measuring the electrocatalytic anodic current of hydrazine caused by the nonspecifically absorbed AuNPs.

Biochem/physiol Actions

GABAB receptor agonist; antagonist of basal prolactin secretion.

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