Geptanolimab
Geptanolimab Basic information
- Product Name:
- Geptanolimab
- Synonyms:
-
- Geptanolimab
- Research Grade Geptanolimab (DHH02224)
- Research Grade Geptanolimab
- Geptanolimab (anti-PDCD1)
- CAS:
- 2348469-43-0
- MW:
- 0
- Mol File:
- Mol File
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Geptanolimab Chemical Properties
- form
- Liquid
- color
- Colorless to light yellow
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Geptanolimab Usage And Synthesis
Uses
Geptanolimab (CBT-501) is a humanized IgG4k monoclonal antibody against programmed death-1 (PD-1). Siplizumab inhibits the binding of PD-L1/L2 to PD-1 through a competitive action. Siplizumab can be used in research of cancer[1].
in vivo
Geptanolimab (ip; once every two weeks, for 6 weeks; mice with MC38 syngeneic tumor models) has anti-tumor activity and tumor inhibition rate reached 83%[1].
References
[1] Qing Z, et, al. Activity of CBT-501, a novel humanized anti-PD-1 antibody, in a humanized genetically engineered mouse model of colon carcinoma. Journal of Clinical Oncology. 2017;35 (7_suppl):108-108.
GeptanolimabSupplier
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
ShangHai Biochempartner Co.,Ltd
- Tel
- 177-54423994 17754423994
- 2853530910@QQ.com
Guangzhou Hongyuan Chemical Co.,Ltd
- Tel
- 15817493340
- 981810490@qq.com
Wuhan Chemstan Biotechnology Co., Ltd.
- Tel
- 027-65317797 15926423062
- 422450190@qq.com
Biolab Reagents
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- 027-65279366 18108604356
- products@biolabreagent.com