(S)-(-)-2-Chloropropionic acid Chemical Properties

Melting point:

4 °C

Boiling point:

77 °C/10 mmHg (lit.)

alpha 

-14.5 º (c=neat)

Density 

1.249 g/mL at 25 °C (lit.)

vapor pressure 

5hPa at 20℃

refractive index 

n20/D 1.436

Flash point:

140 °F

storage temp. 

2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly), Water (Slightly)

pka

2.83(at 25℃)

form 

Liquid

color 

Clear light yellow

Water Solubility 

soluble

BRN 

1720257

LogP

0.82 at 20.5℃

CAS DataBase Reference

29617-66-1(CAS DataBase Reference)

NIST Chemistry Reference

(S)-(-)-2-chloropropionic acid(29617-66-1)

Safety Information

Hazard Codes 

C

Risk Statements 

21/22-35-48/22

Safety Statements 

23-26-28-36/37/39-45

RIDADR 

UN 2511 8/PG 3

WGK Germany 

1

RTECS 

UA2451950

HazardClass 

8

PackingGroup 

III

HS Code 

29159080

MSDS

• Language:English Provider:2-Chloropropanoic acid
• Language:English Provider:SigmaAldrich
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(S)-(-)-2-Chloropropionic acid Usage And Synthesis

Chemical Properties

Colourless Oil

Uses

Through the stereo displacement of (S)-(-)-2-Chloropropionic acid PPAR Agonist can be synthesized via asymmetric hydrogenation of a cinnamic acid derivative.

Definition

ChEBI: A monocarboxylic acid that is propanoic acid substitued at position 2 by a chloro group (the S-enantiomer).

Flammability and Explosibility

Non flammable

Purification Methods

Purify the acid by fractionating twice through a 115cm Podbielniak column (p 11, calculated 50 theoretical plates at atmospheric pressure) using a take-off ratio of 1:5. The acid chloride is prepared by dissolving the acid in SOCl2, adding a few drops of PCl3, refluxing and then distilling through a 30cm column, b 53o/100mm, [] -4.6o (neat), d 1.2689, n1.4368. [Fu et al. J Am Chem Soc 76 6954 1954, Beilstein 2 IV 745.]

(S)-(-)-2-Chloropropionic acid(29617-66-1)Related Product Information

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