Diethyl chloromalonate Chemical Properties

Boiling point:

279.11°C (rough estimate)

Density 

1.204 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.432(lit.)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,2-8°C

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

form 

Liquid

pka

9.07±0.46(Predicted)

color 

Clear colorless

Specific Gravity

1.204

LogP

2.23 at 40℃ and pH4-9

CAS DataBase Reference

14064-10-9(CAS DataBase Reference)

EPA Substance Registry System

Propanedioic acid, 2-chloro-, 1,3-diethyl ester (14064-10-9)

Safety Information

Hazard Codes 

C

Risk Statements 

34-36/37

Safety Statements 

26-27-28-36/37/39-45

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

HazardClass 

8

PackingGroup 

III

HS Code 

29171990

MSDS

• Language:English Provider:Diethyl chloromalonate
• Language:English Provider:SigmaAldrich

Diethyl chloromalonate Usage And Synthesis

Chemical Properties

Clear Colourless Liquid

Uses

A compound used in the models of aquatic toxicity developed (QSAR). Combinatorial QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis.

Uses

Diethyl chloromalonate is a compound used in the models of aquatic toxicity developed

General Description

Diethyl chloromalonate (Diethyl α-chloromalonate) is a 2-halo-1,3-dicarbonyl compound. It participates in K₂CO₃-catalyzed domino reactions (Michael alkylation, Mannich alkylation, and aldol alkylation) of salicylic aldehyde derivatives to afford functionalized 2,3-dihydrobenzofurans. It reacts with Cs₂CO₃ in the presence of elemental S₈ or Se_n to afford the corresponding diethyl thioxo- or selenoxomalonates, which can be trapped in situ with various 1,3-dienes.

Diethyl chloromalonate(14064-10-9)Related Product Information

• Diethyl dibutylmalonate
• Mefenpyr-diethyl
• Methyl acrylate
• Ethyl malonyl chloride
• Ethylene glycol diethyl ether
• Diethyl benzylmalonate
• Diethyl methylmalonate
• Tris(trimethylsilyl)phosphate
• 2-AMINODIETHYLMALONATE
• Diethyl malonate
• Diethyl oxalate
• Dimethyl succinate
• Diethyl fluoromalonate
• Dimethyl chloromalonate
• DIETHYL BROMOMALONATE
• METHYL CHLORODIFLUOROACETATE
• Bosentan Impurity 5
• 2-Cyanopyrimidine