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Fmoc-D-leucine

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Fmoc-D-leucine Basic information

Product Name:
Fmoc-D-leucine
Synonyms:
  • FMOC-D-BETA-LEU-OH
  • FMOC-D-LEU-OH
  • FMOC-D-LEUCINE
  • FMOC-D-LEU
  • 9-FLUORENYLMETHOXYCARBONYL-D-LEUCINE
  • FMOC-D-LEU-OH 99+%
  • n-[(9h-fluoren-9-ylmethoxy)carbonyl]-d-leucine
  • n-fmoc-d-leucine
CAS:
114360-54-2
MF:
C21H23NO4
MW:
353.41
EINECS:
252-662-7
Product Categories:
  • Leucine [Leu, L]
  • Fmoc-Amino Acids and Derivatives
  • Amino Acids (N-Protected)
  • Biochemistry
  • Fmoc-Amino Acids
  • Fmoc-Amino acid series
  • Fluorenes, Flurenones
  • Amino Acids
Mol File:
114360-54-2.mol
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Fmoc-D-leucine Chemical Properties

Melting point:
155°C
Boiling point:
559.8±33.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
refractive index 
25 ° (C=1, DMF)
storage temp. 
2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka
3.91±0.21(Predicted)
form 
powder to crystal
color 
White to Almost white
Water Solubility 
Insoluble in water.
CAS DataBase Reference
114360-54-2(CAS DataBase Reference)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
10
HS Code 
29224999

MSDS

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Fmoc-D-leucine Usage And Synthesis

Chemical Properties

White powder

Uses

A convergent synthesis of the proposed structure of (+)-pestalazine B has been achieved in 4 steps using the N-alkylation of an unprotected tryptophan diketopiperazine with a 3a-bromopyrrolidinoindoline where the condensation between L-tryptophan methyl ester and N-Fmoc-D-leucine in the presence of EDC as coupling agent afforded the corresponding L-Trp-D-Leu dipeptide.

Definition

ChEBI: Fmoc-D-Leu-OH is a leucine derivative.

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