L-tert-Leucine Chemical Properties

Melting point:

≥300 °C (lit.)

alpha 

6.3 º (c=4, 6 N HCl 200 ºC)

Boiling point:

217.7±23.0 °C(Predicted)

Density 

1.1720 (estimate)

refractive index 

-9 ° (C=3, H2O)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

1 M HCl: 50 mg/mL

form 

powder

pka

2.39±0.12(Predicted)

color 

White to almost white

optical activity

[α]20/D 9.5°, c = 3 in H2O

Water Solubility 

125.5 g/L (20 ºC)

BRN 

1721824

InChIKey

NPDBDJFLKKQMCM-SCSAIBSYSA-N

CAS DataBase Reference

20859-02-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Safety Statements 

22-24/25

WGK Germany 

3

RTECS 

OH2850000

Hazard Note 

Irritant

HS Code 

29224999

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

L-tert-Leucine Usage And Synthesis

Description

L-tert-Leucine is an essential amino acid making up one third of our muscle protein. L-tert-leucine is important in developing chiral pharmaceutically active chemicals. It can be used as a food additive. It is used in the formation of sterols. It can also be used as the catalyst in the production of cobalt oxazoline palladacycles complex. It can also be used for the production of Chiral tridentate Schiff base ligands.

References

Korkmaz, Neslihan, D. Astley, and S. T. Astley. "Tridentate ligands derived from L-tert-Leucine for the Cu(II) mediated asymmetric Henry reaction." Turkish Journal of Chemistry 35.3(2011):1-17.
https://www.alfa.com/en/catalog/L13707/
http://igem.org/abstract_pdf_file.cgi?id=1719

Chemical Properties

White to almost white powder

Uses

L-tert-Leucine is an essential amino acid and makes up one third of our muscle protein. It can be used as a food additive. It is used in the formation of sterols. It is used in the production of cobalt oxazoline palladacycles complex, which acts as a catalyst in the rearrangement of prochiral N-aryl trifluoroacetimidates to allylic amides yielded in significantly higher enantioselectivities with the (S)-(pR)-diasteroisomer.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 3, p. 523, 1955
Tetrahedron Letters, 19, p. 4625, 1978 DOI: 10.1016/S0040-4039(01)85688-4

L-tert-Leucine(20859-02-3)Related Product Information

• 6-Aminocaproic acid
• L-Leucine
• N-CARBOBENZOXY-DL-LEUCINE
• tert-Butanol
• (S)-TERT-LEUCINOL
• ALTRENOGEST
• Glycine
• Tris(hydroxymethyl)aminomethane
• DL-Threonine hydrate(2:1)
• L-Tryptophan
• L-Serine
• L-Threonine
• (S)-(+)-2-Amino-3-methyl-1-butanol
• (S)-TERT-LEUCINE,L-Tert-Leucine HCl,DL-TERT-LEUCINE
• L-tert-Leucine methyl ester hydrochloride
• Leucine aminopeptidase，porcine kidney
• CBZL-L-TERT-LEUCINE,CBZ-L-TERT-LEUCINE,N-ALPHA-CARBOBENZOXY-L-TERT-LEUCINE,Z-L-TERT-LEUCINE
• FMOC-L-TERT-LEUCINE,N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-TERT-LEUCINE