VU 0365114 Chemical Properties

Boiling point:

526.2±60.0 °C(Predicted)

Density 

1.386±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Ethanol:10.0(Max Conc. mg/mL);25.17(Max Conc. mM)
DMSO:30.0(Max Conc. mg/mL);75.5(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);75.5(Max Conc. mM)

form 

Powder

pka

-3.71±0.20(Predicted)

color 

Light yellow to orange

VU 0365114 Usage And Synthesis

Uses

VU 0365114 is a selective positive allosteric modulator of M5 (EC50 values are 2.7 μM for human M5, and >30 μM for M1, M2, M3 and M4 receptors).

Definition

ChEBI: 1-[(4-phenylphenyl)methyl]-5-(trifluoromethoxy)indole-2,3-dione is a member of biphenyls.

storage

Store at RT

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