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XL-388

Basic information Safety Supplier Related

XL-388 Basic information

Product Name:
XL-388
Synonyms:
  • Methanone, [7-(6-amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-
  • [7-(6-Amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-methanone XL388
  • XL388, >=98%
  • (7-(6-Aminopyridin-3-yl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)(3-fluoro-2-methyl-4-(methy
  • XL 388
  • XL388
  • XL-388
  • [7-(6-Amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-methanone
CAS:
1251156-08-7
MF:
C23H22FN3O4S
MW:
455.5
Product Categories:
  • PI3K/Akt/mTOR
  • Akt
  • Inhibitors
  • mTOR
  • PI3K
Mol File:
1251156-08-7.mol
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XL-388 Chemical Properties

Melting point:
>188oC (dec.)
Boiling point:
738.6±60.0 °C(Predicted)
Density 
1.354±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
6.22±0.13(Predicted)
form 
Solid
color 
Off-White to Pale Yellow
Stability:
Hygroscopic
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XL-388 Usage And Synthesis

Uses

XL388 is a highly potent, orally bioavailable, selective, ATP-competitive mammalian target of rapamycin (mTOR) inhibitor. XL388 has shown significant and dose-dependent antitumor activity in athymic nude mice implanted with human tumor xenografts.

XL-388Supplier

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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jkinfo@jkchemical.com
Jinan Trio PharmaTech Co., Ltd.
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+86 (531) 88811783
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sales@trio-pharmatech.com (International market)
Dalian Meilun Biotech Co., Ltd.
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0411-62910999 13889544652
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sales@meilune.com
Shanghai Topbiochem Technology Co., Ltd
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021-58170097
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info@topbiochem.com
Haoyuan Chemexpress Co., Ltd.
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021-58950125
Email
info@chemexpress.com
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XL-388(1251156-08-7)Related Product Information