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3-Hydroxy-4-methoxybenzoic acid

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3-Hydroxy-4-methoxybenzoic acid Basic information

Product Name:
3-Hydroxy-4-methoxybenzoic acid
Synonyms:
  • AKOS 220-48
  • 4-METHOXY-3-HYDROXYBENZOIC ACID
  • 3-HYDROXYANISIC ACID
  • 3-HYDROXY-4-METHOXYBENZOIC ACID
  • ISOVANILLIC ACID
  • 3-hydroxy-4-methoxy-benzoicaci
  • RARECHEM AL BE 0068
  • Isovanillic aci
CAS:
645-08-9
MF:
C8H8O4
MW:
168.15
EINECS:
211-430-5
Product Categories:
  • sy
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • Acids and Derivatives
  • Alcohols and Derivatives
  • BenzoicAcidDerivative
  • API intermediates
Mol File:
645-08-9.mol
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3-Hydroxy-4-methoxybenzoic acid Chemical Properties

Melting point:
250-253 °C(lit.)
Boiling point:
257.07°C (rough estimate)
Density 
1.3037 (rough estimate)
refractive index 
1.5090 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
form 
Powder
pka
4.35±0.10(Predicted)
color 
Beige to gray-brown
BRN 
2208365
LogP
1.350 (est)
CAS DataBase Reference
645-08-9(CAS DataBase Reference)
NIST Chemistry Reference
3-Hydroxy-4-methoxybenzoic acid(645-08-9)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
BZ4850000
HazardClass 
IRRITANT
HS Code 
29189900

MSDS

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3-Hydroxy-4-methoxybenzoic acid Usage And Synthesis

Chemical Properties

beige to grey-brown powder

Uses

Isovanillic acid has been used in the synthesis of opiate alkaloid precursor, dihydrothebainone.

Definition

ChEBI: A methoxybenzoic acid that is 4-methoxybenzoic acid bearing a hydroxy substituent at position 3.

General Description

Rate of oxidation of isovanillic acid by washed cells of Pseudomonas putida has been reported.

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