ChemicalBook > CAS DataBase List > 3-Hydroxy-4-methoxybenzoic acid

3-Hydroxy-4-methoxybenzoic acid

Product Name
3-Hydroxy-4-methoxybenzoic acid
CAS No.
645-08-9
Chemical Name
3-Hydroxy-4-methoxybenzoic acid
Synonyms
ISOVANILLIC ACID;AKOS 220-48;Thenblueacid;Isovanillic aci;Diosmin Impurity A;Diosmin Impurity 1;acideisovanillique;IsovanillicAcid>RARECHEM AL BE 0068;Diosmin Impurity 10
CBNumber
CB3303201
Molecular Formula
C8H8O4
Formula Weight
168.15
MOL File
645-08-9.mol
More
Less

3-Hydroxy-4-methoxybenzoic acid Property

Melting point:
250-253 °C(lit.)
Boiling point:
257.07°C (rough estimate)
Density 
1.3037 (rough estimate)
refractive index 
1.5090 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
form 
Powder
pka
4.35±0.10(Predicted)
color 
Beige to gray-brown
BRN 
2208365
InChI
1S/C8H8O4/c1-12-7-3-2-5(8(10)11)4-6(7)9/h2-4,9H,1H3,(H,10,11)
InChIKey
LBKFGYZQBSGRHY-UHFFFAOYSA-N
SMILES
COc1ccc(cc1O)C(O)=O
LogP
1.350 (est)
CAS DataBase Reference
645-08-9(CAS DataBase Reference)
NIST Chemistry Reference
3-Hydroxy-4-methoxybenzoic acid(645-08-9)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
BZ4850000
HazardClass 
IRRITANT
HS Code 
29189900
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
I0295
Product name
Isovanillic Acid
Purity
>98.0%(HPLC)(T)
Packaging
10g
Price
$79
Updated
2021/12/16
TCI Chemical
Product number
I0295
Product name
Isovanillic Acid
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$161
Updated
2025/07/31
TCI Chemical
Product number
I0295
Product name
Isovanillic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$51
Updated
2025/07/31
TRC
Product number
H972638
Product name
3-Hydroxy-4-methoxybenzoicacid
Packaging
1g
Price
$55
Updated
2021/12/16
Matrix Scientific
Product number
063756
Product name
3-Hydroxy-4-methoxybenzoic acid
Packaging
25g
Price
$72
Updated
2021/12/16
More
Less

3-Hydroxy-4-methoxybenzoic acid Chemical Properties,Usage,Production

Chemical Properties

beige to grey-brown powder

Uses

Isovanillic acid has been used in the synthesis of opiate alkaloid precursor, dihydrothebainone.

Definition

ChEBI: A methoxybenzoic acid that is 4-methoxybenzoic acid bearing a hydroxy substituent at position 3.

General Description

Rate of oxidation of isovanillic acid by washed cells of Pseudomonas putida has been reported.

3-Hydroxy-4-methoxybenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-Hydroxy-4-methoxybenzoic acid Suppliers

SICHUAN JILONGXINGRUI PHARMA CO,.LTD
Tel
0830-8999890 13883082125
Email
511598975@qq.com
Country
China
ProdList
13
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
More
Less

View Lastest Price from 3-Hydroxy-4-methoxybenzoic acid manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
3-Hydroxy-4-methoxybenzoic acid 645-08-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-15
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
3-Hydroxy-4-methoxybenzoic acid 645-08-9
Price
US $200.00-95.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-24
Henan Aochuang Chemical Co.,Ltd.
Product
3-Hydroxy-4-methoxybenzoic acid 645-08-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-10

645-08-9, 3-Hydroxy-4-methoxybenzoic acidRelated Search:


  • AKOS 220-48
  • 4-METHOXY-3-HYDROXYBENZOIC ACID
  • 3-HYDROXYANISIC ACID
  • 3-HYDROXY-4-METHOXYBENZOIC ACID
  • ISOVANILLIC ACID
  • 3-hydroxy-4-methoxy-benzoicaci
  • RARECHEM AL BE 0068
  • Isovanillic aci
  • 4-Carboxy-2-hydroxyanisole, Isovanillic acid, 2-Methoxy-5-carboxyphenol, 5-Carboxyguaiacol, 3-Hydroxy-p-anisic acid
  • Thenblueacid
  • Diosmin Impurity A
  • Diosmin Impurity 10
  • Diosmin Impurity 1
  • 3-hydroxy-p-anisicaci
  • Acide isovanillique
  • acideisovanillique
  • Benzoic acid, 3-hydroxy-4-methoxy-
  • p-Anisic acid, 3-hydroxy-
  • ISOVANILLIC ACID (3-HYDROXY-4-METHOXYBENZOIC ACID)
  • 3-Hydroxy-4-methoxybenzoic acid, 97+%
  • 5-Carboxy-2-methoxyphenol
  • 3-Hydroxy-4-methoxybenzoic acid,99%
  • 3-hydroxy-p-anisic acid
  • 3-Hydroxy-4-Methoxybenzoic
  • 3-Hydroxy-4-Methoxybenzoic acid, 99% 5GR
  • 4-Carboxy-2-hydroxyanisole, Isovanillic acid
  • IsovanillicAcid&gt
  • Isovanillic acid,97%
  • Diossmin impurity 19
  • Isovanillic acid, 10 mM in DMSO
  • 645-08-9
  • HOC6H3OCH3CO2H
  • Organic Building Blocks
  • Building Blocks
  • C8
  • Carbonyl Compounds
  • Carboxylic Acids
  • sy
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • BenzoicAcidDerivative
  • Acids and Derivatives
  • Alcohols and Derivatives
  • API intermediates