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7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine

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7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine Basic information

Product Name:
7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine
Synonyms:
  • 7-Iodo-7-Deaza-2',3'-dideoxyguanosine
  • 7-Deaza-7-I-ddG
  • 2-Amino-7-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodo-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
  • 7-Deaza-2',3'-dideoxy-7-iodoguanosine
  • 7-I-7-Deaza-ddG
  • 2-Amino-3,7-dihydro-5-iodo-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-4H-pyrrolo[2,3-d]pyrimidin-4-one
  • 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-3,7-dihydro-5-iodo-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-7-Deaza-2'3'-dideoxy-7-iodoguanosine
  • 7-Iodo-2',3'-Dideoxy-7-Deaza-D-Guanosine
CAS:
114748-67-3
MF:
C11H13IN4O3
MW:
376.15
EINECS:
500-100-4
Mol File:
114748-67-3.mol
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7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine Chemical Properties

Density 
2.35±0.1 g/cm3(Predicted)
storage temp. 
4°C, protect from light
pka
10.28±0.20(Predicted)
form 
Solid
color 
Off-white to light yellow
InChI
InChI=1S/C11H13IN4O3/c12-6-3-16(7-2-1-5(4-17)19-7)9-8(6)10(18)15-11(13)14-9/h3,5,7,17H,1-2,4H2,(H3,13,14,15,18)/t5-,7+/m0/s1
InChIKey
KJNOBXXCZQLWLF-CAHLUQPWSA-N
SMILES
C1(N)NC(=O)C2C(I)=CN([C@H]3CC[C@@H](CO)O3)C=2N=1
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7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine Usage And Synthesis

Uses

7-Iodo-2',3'-dideoxy-7-deaza-guanosine is a dideoxynucleoside that can be used in DNA synthesis and sequencing reactions[1].

References

[1] Gene Shen, et al. Thiotriphosphate nucleotide dye terminators for use in nucleic acid sequencing. US20060281100A1.

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