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1-(3-Chlorophenyl)piperazine hydrochloride

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1-(3-Chlorophenyl)piperazine hydrochloride Basic information

Product Name:
1-(3-Chlorophenyl)piperazine hydrochloride
Synonyms:
  • 1-(3-CHLOROPHENYL)PIPERAZINE 2HCL
  • 1-(3-Chlorophenyl)piperazine hydrochloride,97%
  • N-(3-Chlorophenyl) Piperazine HCl
  • 1-(3-Chlorophenyl)piperazine hydrochloride
  • 1-(3-CHLOROPHENYL)-PIPERAZINE HCL (MCLPPB)
  • Piperazine, 1-(3-chlorophenyl)-, hydrochloride
  • 1-(3-Chlorophenyl)piperidine/hydrochloric acid,(1:x)
  • 1-(3-Chlorophenyl)piperazine hydrochloride ,98%
CAS:
65369-76-8
MF:
C10H14Cl2N2
MW:
233.14
EINECS:
265-718-0
Product Categories:
  • Serotonin receptor
  • Piperazines
  • API intermediates
Mol File:
65369-76-8.mol
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1-(3-Chlorophenyl)piperazine hydrochloride Chemical Properties

Melting point:
210-214 °C (dec.)(lit.)
Density 
1,193g/cm
refractive index 
1,598-1,600
Flash point:
9℃
storage temp. 
Store at RT
solubility 
methanol: soluble
form 
Solid
color 
Pale brown
Stability:
Hygroscopic
CAS DataBase Reference
65369-76-8(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,Xn,T,F
Risk Statements 
36/37/38-22-39/23/24/25-23/24/25-11
Safety Statements 
26-36-24/25-45-36/37-16-7
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900

MSDS

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1-(3-Chlorophenyl)piperazine hydrochloride Usage And Synthesis

Chemical Properties

Off-white solid

Uses

Chlorophenyl Piperazine Hydrochloride Salt is a useful intermediate for organic synthesis and other chemical properties. Trazodone impurity.

General Description

1-(3-Chlorophenyl)-piperazine, also known as meta-chlorophenylpiperazine or mCPP, is a designer drug analog of aryl-substituted piperazines. A stimulant, serotonin antagonist and reuptake inhibitor (SARU), mCPP can also be detected as a primary urinary metabolite of the antidepressant drug trazadone. This certified solution standard is suitable for use in piperazine testing methods by LC/MS or GC/MS for clinical toxicology, forensic analysis, or urine drug testing applications.

Biological Activity

5-HT 2C/2B receptor agonist/partial agonist; displays some activity at 5-HT 2A and 5-HT 1 receptors. pEC 50 values are 7.09, 7.2, 6.65, 5.9 and 6.5 for human recombinant 5-HT 2C , 2B and 2A , bovine 5-HT 1A and rat 5-HT 1B receptors respectively. Suppresses locomotor activity in rats in vivo .

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