PHENYLGLYOXAL Chemical Properties

Melting point:

~76 °C

Boiling point:

142°C/125mmHg

Density 

1.133±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

BRN 

1854721

InChI

InChI=1S/C8H6O2/c9-6-8(10)7-4-2-1-3-5-7/h1-6H

InChIKey

OJUGVDODNPJEEC-UHFFFAOYSA-N

SMILES

C1(=CC=CC=C1)C(=O)C=O

CAS DataBase Reference

1074-12-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/37/38-41

Safety Statements 

22-26-36-39

WGK Germany 

3

RTECS 

MD3260000

HS Code 

29122900

PHENYLGLYOXAL Usage And Synthesis

Chemical Properties

white to light yellow powder

Definition

ChEBI: Phenylglyoxal is a member of phenylacetaldehydes.

Synthesis Reference(s)

The Journal of Organic Chemistry, 53, p. 830, 1988 DOI: 10.1021/jo00239a027
Tetrahedron Letters, 27, p. 5139, 1986 DOI: 10.1016/S0040-4039(00)85154-0

Enzyme inhibitor

This commercially available peptide/protein-modifying reagent (FW = 134.13 g/mol; CAS 1074-12-0), occasionally called benzoylformaldehyde, is a mild oxidant that reacts covalently with guanidinium groups at pH ~ 7, consuming two moles of reagent per mole of reactive arginyl residue. Modified guanidinium groups are relatively stable below pH 4; however, the original guanidinium group is slowly regenerated at neutral or alkaline pH. Upon prolonged incubation with phenylglyoxal, a-amino groups may also be modified. See also Glyoxal; 4-Hydroxyphenylglyoxal; etc. Target(s): To date, over 240 enzymes are inhibited by phenylglyoxal

PHENYLGLYOXAL(1074-12-0)Related Product Information

• 5-Methylisatin
• 5-Bromoisatin
• Benzoylformic acid
• POTASSIUM 1,2-NAPHTHOQUINONE-4-SULFONIC ACID
• 4,4'-DIMETHOXYBENZIL
• Acenaphthenequinone
• 1-Phenyl-1,2-propanedione
• N-METHYLISATIN
• Benzil
• Phenanthrenequinone
• PHENYLGLYOXAL
• 1,2-NAPHTHOQUINONE-4-SULFONIC ACID SODIUM SALT
• Methyl benzoylformate
• 5-Nitroisatin
• 4,4'-DIMETHYLBENZIL
• Ethyl benzoylformate
• 1,2-NAPHTHOQUINONE
• PHENYLGLYOXAL DIETHYL ACETAL,PHENYLGLYOXAL 2-DIETHYL ACETAL,α,α-Diethoxyacetophenone, Phenylglyoxal 2-diethyl acetal