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Homocystine

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Homocystine Basic information

Product Name:
Homocystine
Synonyms:
  • 2-ammonio-4-[(3-ammonio-3-carboxylatopropyl)disulfanyl]butanoate
  • 4,4'-Disulfanediylbis(2-aMinobutanoic acid)
  • Product NameL-homocystine Synonyms
  • 4,4'-dithiobis[2-aminobutyric] acid
  • 4,4'-dithiobis[2-amino-Butanoic acid]
  • L-4,4'-Dithiobis(2-aminobutyric acid)
  • Butanoic acid, 4,4'-dithiobis[2-amino-
  • DL-HOMOCYSTINE
CAS:
462-10-2
MF:
C8H16N2O4S2
MW:
268.35
EINECS:
207-323-8
Mol File:
462-10-2.mol
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Homocystine Chemical Properties

Melting point:
281-284°C (dec.)
alpha 
77 º (c=1%,1N HCl)
Boiling point:
507.6±50.0 °C(Predicted)
Density 
1.443±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Aqueous Acid (Slightly). Aqueous Base (Slightly)
form 
Solid
pka
1.90±0.10(Predicted)
color 
White to Off-White
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Safety Information

Safety Statements 
22-24/25
HS Code 
2930909899
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Homocystine Usage And Synthesis

Uses

DL-Homocystine is used in the synthesis of potential antitumor agents through inhibition of L-asparagine. There is growing clinical evidence that elevated homocysteine levels are associated with an increased risk of venous and arterial thrombosis.

Definition

ChEBI: An organic disulfide obtained by oxidative dimerisation of homocysteine.

Purification Methods

dl-Homocystine crystallises in platelets from water with 1H2O and m 258-260o(dec), all operations should be carried out under N2. [Sudo J Chem Soc Jpn (Pure Chem Sect) 79 81, 86, 87 1958, Beilstein 4 IV 3199.]

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