2-Chloro-4-methoxypyridine Chemical Properties

Boiling point:

224-225 °C (lit.)

Density 

1.258 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.5400(lit.)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Soluble in alcohol.

form 

Liquid

pka

2.25±0.10(Predicted)

Specific Gravity

1.258

color 

Colorless to pale yellow

BRN 

1423379

InChIKey

PMTPFBWHUOWTNN-UHFFFAOYSA-N

CAS DataBase Reference

17228-69-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37

RIDADR 

2810

WGK Germany 

3

PackingGroup 

III

HS Code 

29333990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Chloro-4-methoxypyridine Usage And Synthesis

Chemical Properties

Colorless liquid

Uses

It is an active pharmaceutical ingredient.

Uses

2-Chloro-4-methoxypyridine may be used to synthesize:

• 2-(2′,4′-difluorophenyl)-4-methoxypyridine
• (2-chloro-4-methoxypyridin-3-yl)bis-[2-(methylsulfanyl)pyrimidin-4-yl]methanol
• (2-chloro-4-methoxypyridin-3-yl)bis-[2-(methylsulfanyl) pyrimidin-4-yl]methyl acetate

General Description

2-Chloro-4-methoxypyridine can be obtained from the reaction between 2-chloro-4-nitropyridine and sodium methoxide in the presence of dioxane. It can also be prepared starting from 4-methoxy-2(1H)-pyridone and 4-nitropyridine N-oxide.

2-Chloro-4-methoxypyridine(17228-69-2)Related Product Information

• 4-Methoxypyridine
• 2-Chloro-5-chloromethylpyridine
• 2-Chloro-4-picoline
• Clopidol
• 4-Methoxybenzylchloride
• 2-CHLORO-4-METHOXYPYRIMIDINE
• 2-CHLORO-4-METHOXYNICOTINONITRILE
• 2-CHLORO-6-METHOXYPYRIDINE,6-Chloro-2-methoxypyridine,2-Chloro-6-methoxypyridine, GC 98%
• Difluorochloromethane
• 2-CHLORO-4-METHOXY-3-NITROPYRIDINE
• 2-CHLORO-3,5-DIMETHYL-4-METHOXY PYRIDINE HYDROCHLORIDE
• 6-CHLORO-4-ETHOXYNICOTINIC ACID
• 3-Chloro-2-methoxypyridine 98%,3-CHLORO-2-METHOXYPYRIDINE
• 5-CHLORO-2-METHOXYPYRIDINE
• 2-Chloro-3-methoxypyridine ,98%,2-CHLORO-3-METHOXYPYRIDINE
• 3-Bromo-2-methoxy-5-trifluoromethylpyridine
• 3-CHLORO-2-METHOXYPYRIDINE-5-BORONIC ACID
• 2-Chloro-5-methoxypyridine-3-boronic acid,2-Chloro-5-methoxypyridine-4-boronic acid,2-Chloro-4-methoxypyridine-3-boronic acid