2-Chlorothiazole Chemical Properties

Melting point:

85 °C

Boiling point:

145 °C

Density 

1.393 g/mL at 25 °C

refractive index 

n20/D1.551

Flash point:

54℃

storage temp. 

Inert atmosphere,2-8°C

solubility 

soluble in Ether

form 

clear liquid

pka

0.84±0.10(Predicted)

color 

Colorless to Almost colorless

InChI

InChI=1S/C3H2ClNS/c4-3-5-1-2-6-3/h1-2H

InChIKey

KLEYVGWAORGTIT-UHFFFAOYSA-N

SMILES

S1C=CN=C1Cl

CAS DataBase Reference

3034-52-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

20/21/22-36/37/38-41-22-10

Safety Statements 

23-26-36/37/39-39

RIDADR 

1993

WGK Germany 

1

HazardClass 

3

PackingGroup 

Ⅲ

HS Code 

2934100090

MSDS

• Language:English Provider:ALFA

2-Chlorothiazole Usage And Synthesis

Chemical Properties

Pale yellow liquid

Definition

ChEBI: 2-chlorothiazole is a member of 1,3-thiazoles and an organochlorine compound.

Reactivity Profile

Halogen atoms in the 4- and 5-positions of thiazoles exhibit different reactivities depending on the nucleophile: with methoxide ion in methanol the reactivity sequence is 5-chlorothiazole > 2-chlorothiazole > 4-chlorothiazole. In contrast, with thiophenoxide ion or piperidine in methanol, the sequence 2 > 4 > 5 is observed. With the series of alkoxide ions methoxide, ethoxide, isopropoxide and t-butoxide in the corresponding alcohol, the reactivity ratios of 4-chlorothiazole versus 2-chlorothiazole are: 0.07, 0.6, 4, 42. The nucleophilic reactivity of 2-halogenothiazoles is strongly affected by substituents: 2-chloro-5-nitrothiazole is more reactive than 2-chlorothiazole by a factor of 10.

2-Chlorothiazole(3034-52-4)Related Product Information

• Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT)
• Thiazole
• 2,2'-Dithiobis(benzothiazole)
• Fosthiazate
• Benzothiazole
• Epichlorohydrin
• 2-(2-Aminothiazol-4-yl)glyoxylic acid
• 2-Mercaptobenzothiazole
• 2-Chlorobenzothiazole
• Difluorochloromethane
• 2,6-Dichlorobenzothiazole
• 2-Chloro-6-nitrobenzothiazole
• 2-CHLORO-4-METHYL-THIAZOLE
• Benzothiazole, 2,5-dichloro- (7CI,8CI,9CI)
• 2,4-Dichlorobenzothiazole
• Chloroacetic acid
• 2-Chloro-6-methoxybenzothiazole
• 2,4-Dichloro-5-thiazolecarboxaldehyde