(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid Chemical Properties

Melting point:

146-151 °C

alpha 

+48～+52°(c=0.67,MeOH,24℃)

Boiling point:

390.9±42.0 °C(Predicted)

Density 

1.312

storage temp. 

2-8°C

pka

3.80±0.40(Predicted)

form 

powder to crystal

color 

White to Light yellow

optical activity

[α]22/D +50.0°, c = 1 in methanol

InChIKey

BENKAPCDIOILGV-RNFRBKRXSA-N

Safety Information

Hazard Codes 

Xi

Risk Statements 

36

Safety Statements 

26

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29339900

(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid Usage And Synthesis

Chemical Properties

White solid

Uses

N-Boc-cis-4-hydroxy-D-proline can be used:

• As a starting material in the synthesis of DNA mimicking pyrrolidine peptide nucleic acid (PNA) analog.
• In the synthesis of biologically important macrocyclic dilactones.
• As an intermediate in the synthesis of histamine H₃?receptor antagonists.

(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid(135042-12-5)Related Product Information

• tert-Butyl peroxyacetate
• OXALIC ACID
• Salicylic acid
• L-PROLINE-(4-3H(N))
• BOC-L-Proline
• 2,3,4-Trihydroxybenzoic acid
• trans-4-Hydroxy-D-proline
• tert-Butanol
• Ethyl 2-(Chlorosulfonyl)acetate
• 2'-Hydroxy-3-phenylpropiophenone
• Folic acid
• Citric acid
• cis-4-Hydroxy-L-proline
• BUTYL OLEATE
• Buprofezin
• Butyl acetate
• Cyhalofop-butyl
• 4-Hydroxybenzoic acid