Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  API >  Antibiotics >  Aminoglycosides drugs >  Ribostamycin sulfate

Ribostamycin sulfate

Basic information Safety Supplier Related

Ribostamycin sulfate Basic information

Product Name:
Ribostamycin sulfate
Synonyms:
  • Rribostamycin sulfate
  • Ribostamycin sulfate
  • D-Streptamine, O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-O-[β-D-ribofuranosyl-(1→5)]-2-deoxy-, sulfate (1:1)
  • Ribose neoMycin sulfate
  • Ribostamycin s
  • DTDP-GLUCOSE, DISODIUM SALT
  • landamycine
  • o-2,6-diamino-2,6-dideoxy-alpha-d-glucopyranosyl-(1-4)-o-(beta-d-streptamin
CAS:
53797-35-6
MF:
C17H36N4O14S
MW:
552.55
EINECS:
258-783-1
Product Categories:
  • Antibiotics
  • AminoglycosidesAntibiotics
  • Antibacterial
  • Antibiotics A to
  • Antibiotics by Application
  • Antibiotics N-SAntibiotics
  • Chemical Structure Class
  • Genetic Marker SelectionAntibiotics
  • Interferes with Protein SynthesisSpectrum of Activity
  • L - Z
  • Mechanism of Action
Mol File:
53797-35-6.mol
More
Less

Ribostamycin sulfate Chemical Properties

Melting point:
175-180 C
alpha 
D20 +39° (c = 1)
Flash point:
>110°(230°F)
storage temp. 
Inert atmosphere,2-8°C
solubility 
H2O: soluble50mg/mL
form 
powder
color 
White to Off-White
Water Solubility 
Soluble in water
Merck 
14,8206
Stability:
Hygroscopic
More
Less

Safety Information

Hazard Codes 
T,Xi
Risk Statements 
61-20/21/22-36/38
Safety Statements 
53-22-36/37/39-45-37/39-26
WGK Germany 
3
RTECS 
WK2300000
HS Code 
2941.90.1010
Toxicity
LD50 i.v. in mice: 225 mg/kg (Shomura)
More
Less

Ribostamycin sulfate Usage And Synthesis

Uses

Antibacterial;Ribosomal protein synthesis inhibitor

Uses

Ribostamycin is a broad-spectrum antimicrobial isolated from Streptomyces ribosifidicus. It is used in pharmacokinetic and nephrotoxicity studies.

Definition

ChEBI: An aminoglycoside sulfate salt resulting from the reaction of ribostamycin with sulfuric acid.

Biological Activity

Aminoglycosides, such as ribostamycin, bind to the bacterial 30S and 50S ribosomal subunit, which inhibits the translocation of the peptidyl-tRNA from the A-site to the P-site. This causes misreading of mRNA which makes bacteria unable to make essential proteins. It also inhibits the chaperone activity of protein disulfide isomerase (PDI).

Ribostamycin sulfateSupplier

Wuxi Fortune Pharmaceutical Co., Ltd. Gold
Tel
0510-83103151
Email
sales@wuxifortune.com.cn
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Email
info@yuhaochemical.com
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Email
buy@fortunachem.com
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com