Ribostamycin sulfate
Ribostamycin sulfate Basic information
- Product Name:
- Ribostamycin sulfate
- Synonyms:
-
- Rribostamycin sulfate
- Ribostamycin sulfate
- D-Streptamine, O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-O-[β-D-ribofuranosyl-(1→5)]-2-deoxy-, sulfate (1:1)
- Ribose neoMycin sulfate
- Ribostamycin s
- DTDP-GLUCOSE, DISODIUM SALT
- landamycine
- o-2,6-diamino-2,6-dideoxy-alpha-d-glucopyranosyl-(1-4)-o-(beta-d-streptamin
- CAS:
- 53797-35-6
- MF:
- C17H36N4O14S
- MW:
- 552.55
- EINECS:
- 258-783-1
- Product Categories:
-
- Antibiotics
- AminoglycosidesAntibiotics
- Antibacterial
- Antibiotics A to
- Antibiotics by Application
- Antibiotics N-SAntibiotics
- Chemical Structure Class
- Genetic Marker SelectionAntibiotics
- Interferes with Protein SynthesisSpectrum of Activity
- L - Z
- Mechanism of Action
- Mol File:
- 53797-35-6.mol
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Ribostamycin sulfate Chemical Properties
- Melting point:
- 175-180 C
- alpha
- D20 +39° (c = 1)
- Flash point:
- >110°(230°F)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- H2O: soluble50mg/mL
- form
- powder
- color
- White to Off-White
- Water Solubility
- Soluble in water
- Merck
- 14,8206
- Stability:
- Hygroscopic
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Safety Information
- Hazard Codes
- T,Xi
- Risk Statements
- 61-20/21/22-36/38
- Safety Statements
- 53-22-36/37/39-45-37/39-26
- WGK Germany
- 3
- RTECS
- WK2300000
- HS Code
- 2941.90.1010
- Toxicity
- LD50 i.v. in mice: 225 mg/kg (Shomura)
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Ribostamycin sulfate Usage And Synthesis
Uses
Antibacterial;Ribosomal protein synthesis inhibitor
Uses
Ribostamycin is a broad-spectrum antimicrobial isolated from Streptomyces ribosifidicus. It is used in pharmacokinetic and nephrotoxicity studies.
Definition
ChEBI: An aminoglycoside sulfate salt resulting from the reaction of ribostamycin with sulfuric acid.
Biological Activity
Aminoglycosides, such as ribostamycin, bind to the bacterial 30S and 50S ribosomal subunit, which inhibits the translocation of the peptidyl-tRNA from the A-site to the P-site. This causes misreading of mRNA which makes bacteria unable to make essential proteins. It also inhibits the chaperone activity of protein disulfide isomerase (PDI).
Ribostamycin sulfateSupplier
Wuxi Fortune Pharmaceutical Co., Ltd. Gold
- Tel
- 0510-83103151
- sales@wuxifortune.com.cn
XiaoGan ShenYuan ChemPharm co,ltd
- Tel
- 15527768850
- 1791901229@qq.com
Hangzhou Yuhao Chemical Technology Co., Ltd
- Tel
- 0571-82693216
- info@yuhaochemical.com
Wuhan Fortuna Chemical Co., Ltd
- Tel
- 027-59207852 13308628970
- buy@fortunachem.com
Dalian Meilun Biotech Co., Ltd.
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
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Ribostamycin sulfate(53797-35-6)Related Product Information
- Vanadyl sulfate
- Ribose
- Ribonucleic acid
- Apramycin sulfate
- MICRONOMICIN SULFATE
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- Zinc sulfate heptahydrate
- Neomycin sulfate
- Magnesium sulfate heptahydrate
- Sodium sulfate
- Gentamicin sulfate
- D-Ribose
- Ammonium sulfate
- Barium sulfate
- Kanamycin sulfate
- Aluminum sulfate
- sulfate
- 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE