4-Bromo-2,6-difluoroaniline Chemical Properties

Melting point:

63-65 °C (lit.)

Boiling point:

188.2±35.0 °C(Predicted)

Density 

1.788±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

pka

1.11±0.10(Predicted)

form 

Crystalline Powder

color 

Brown

InChI

InChI=1S/C6H4BrF2N/c7-3-1-4(8)6(10)5(9)2-3/h1-2H,10H2

InChIKey

BFQSQUAVMNHOEF-UHFFFAOYSA-N

SMILES

C1(N)=C(F)C=C(Br)C=C1F

CAS DataBase Reference

67567-26-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-36-36/37/39-22

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29214200

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

4-Bromo-2,6-difluoroaniline Usage And Synthesis

Chemical Properties

Off-white crystalline

Uses

4-Bromo-2,6-difluoroaniline was used in synthesis of:

• ammonium 5-bromo-7-fluorobenzo-2-oxa-1,3-diazole-4-sulphonate, fluorogenic derivatizating reagent for the determination of aminothiols by HPLC
• olefin tolanes
• 1-(4-amino-3,5-difluoro)-2-(4-butyloxyphenyl)ethyne
• 4′′-n-butyloxy-3,5-difluoroterphenyl-4-amine
• 4-(3-methylbut-1-yn-3-ol)-2,6-difluoroaniline

Uses

4-Bromo-2,6-difluoroaniline is used in the preparation of potent, VEGF receptor tyrosine kinase inhibitors.

4-Bromo-2,6-difluoroaniline(67567-26-4)Related Product Information

• 4-(Trifluoromethoxy)aniline
• 2,6-Difluoroaniline
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• 2-Fluoroaniline
• 4-Fluoroaniline
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• 4-Bromoaniline
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• Bromine
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