Basic information Safety Supplier Related

H2N-PEG12-CH2CH2NH2

Basic information Safety Supplier Related

H2N-PEG12-CH2CH2NH2 Basic information

Product Name:
H2N-PEG12-CH2CH2NH2
Synonyms:
  • H2N-PEG12-CH2CH2NH2
  • H2N-PEG12-NH2
  • PEODA13
  • Amino-PEG-12-amine,PROTAC Linkers,inhibit,AminoPEG12amine,Amino PEG12 amine,Inhibitor
  • H2N-PEG12-CH2CH2NH2/3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaoctatriacontane-1,38-diamine
  • 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaoctatriacontane-1,38-diamine
CAS:
361543-12-6
MF:
C26H56N2O12
MW:
588.73
Product Categories:
  • peg
Mol File:
361543-12-6.mol
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H2N-PEG12-CH2CH2NH2 Chemical Properties

Boiling point:
621.3±50.0 °C(Predicted)
Density 
1.087±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, protect from light
pka
9.04±0.10(Predicted)
form 
Solid-Liquid Mixture
color 
Colorless to off-white
InChI
InChI=1S/C26H56N2O12/c27-1-3-29-5-7-31-9-11-33-13-15-35-17-19-37-21-23-39-25-26-40-24-22-38-20-18-36-16-14-34-12-10-32-8-6-30-4-2-28/h1-28H2
InChIKey
LBBOTXXNKBSUJN-UHFFFAOYSA-N
SMILES
C(N)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
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H2N-PEG12-CH2CH2NH2 Usage And Synthesis

Uses

Amino-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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