ELEUTHEROSIDE B1(RG)
ELEUTHEROSIDE B1(RG) Basic information
- Product Name:
- ELEUTHEROSIDE B1(RG)
- Synonyms:
-
- ELEUTHEROSIDE B1(RG)
- 2H-1-Benzopyran-2-one,7-(a-D-glucopyranosyloxy)-6,8-dimethoxy-
- 2H-1-Benzopyran-2-one, 7-(α-D-glucopyranosyloxy)-6,8-dimethoxy-
- 6,8-Dimethoxy-7-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one
- Eleutheroside B 1,Influenza Virus,anti-inflammatory,virus,host,Eleutheroside B1,anti-influenza,Eleutheroside B-1,Inhibitor,genes,biosynthesis,inhibit
- CAS:
- 16845-16-2
- MF:
- C17H20O10
- MW:
- 384.34
- Mol File:
- 16845-16-2.mol
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ELEUTHEROSIDE B1(RG) Chemical Properties
- Boiling point:
- 675.0±55.0 °C(Predicted)
- Density
- 1.524±0.06 g/cm3(Predicted)
- storage temp.
- 4°C, away from moisture and light
- pka
- 12.65±0.70(Predicted)
- form
- Solid
- color
- White to off-white
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ELEUTHEROSIDE B1(RG) Usage And Synthesis
Chemical Properties
White crystalline powder, soluble in chloroform, derived from the dried rhizome of Acanthopanax senticosus.
Biological Activity
Eleutheroside B1, a coumarin compound, has broad-spectrum anti-human influenza virus (influenza virus) activity with IC50 values of 64-125μg/ml. It mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits mRNA expression of multiple chemokine genes and influenza virus nucleoprotein (NP) gene with low cytotoxicity. Has antiviral and anti-inflammatory activity.
in vitro
Eeutheroside B1 (100 μg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells.
RT-PCR
| Cell Line: | Virus-infected A549 cells |
| Concentration: | 100 μg/ml |
| Incubation Time: | 24 hours |
| Result: | The expression of host genes (MAN2A2, POLR2A) and virus genes (PA, PB1, PB2, HA) were decreased. |
ELEUTHEROSIDE B1(RG)Supplier
Chengdu Biopurify Phytochemicals Ltd.
- Tel
- +86-028-82633397 18982077548
- cwb1@biopurify.cn
Shanghai Tauto Biotech Co., Ltd.
- Tel
- 021-51320588
- tauto@tautobiotech.com
Chengdu Herbpurify Co.Ltd.
- Tel
- 18302802153 18981717076
- 2355253619@qq.com
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 18892239720
- psaitong@jm-bio.com
Shanghai Yihe Biological Technology Co., Ltd.
- Tel
- 17721395025
- 2423903095@qq.com
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ELEUTHEROSIDE B1(RG)(16845-16-2)Related Product Information
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- Ciwujianoside A1
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