3,6,9,12,15,18,21,24,27,30,33,36,39,42-tetradecaoxatetratetracontane-1,44-diol Chemical Properties

Boiling point:

687.9±50.0 °C(Predicted)

Density 

1.116±0.06 g/cm3(Predicted)

storage temp. 

Store at Room Tem.

pka

14.06±0.10(Predicted)

3,6,9,12,15,18,21,24,27,30,33,36,39,42-tetradecaoxatetratetracontane-1,44-diol Usage And Synthesis

Description

PEG16 is a polymeric structure consisting of ethylene glycol units and two terminal hydroxyl groups. The hydroxyl group can react to further derivatize the compound. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media. The water solubility properties of the PEG linker are enhanced with longer PEG chains.

Uses

HO-PEG15-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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