PEG18 Chemical Properties

Boiling point:

740.9±55.0 °C(Predicted)

Density 

1.117±0.06 g/cm3(Predicted)

storage temp. 

2-8°C, sealed storage, away from moisture and light

solubility 

Soluble in Water, DMSO, DCM, DMF

pka

14.06±0.10(Predicted)

form 

Solid

color 

White to off-white

PEG18 Usage And Synthesis

Description

PEG18 contains repeating ethylene glycol subunits and two terminal hydroxyl groups. The hydroxyl groups can participate in reactions to further derivatize the compound. The hydrophilic PEG chain increases the water solubility of the compound in aqueous media. The water solubility properties of the PEG linker are enhanced with longer PEG chains.

Uses

HO-PEG17-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

PEG18(351342-04-6)Related Product Information

• HEPTAETHYLENE GLYCOL
• Nonaethylene glycol
• HO-PEG18-OH
• PEG21
• HO-PEG14-OH
• Decaethylene glycol
• DODECAETHYLENE GLYCOL
• 3,6,9,12,15,18,21,24,27,30-decaoxadotriacontane-1,32-diol
• 3,6,9,12,15,18,21,24,27,30,33,36,39,42-tetradecaoxatetratetracontane-1,44-diol
• 3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontane-1,38-diol