3,6,9,12,15,18,21,24,27,30-decaoxadotriacontane-1,32-diol Chemical Properties

Boiling point:

571.4±45.0 °C(Predicted)

Density 

1.116±0.06 g/cm3(Predicted)

storage temp. 

Storage temp. 2-8°C

pka

14.06±0.10(Predicted)

form 

Liquid

color 

Colorless to light yellow

InChI

InChI=1S/C22H46O12/c23-1-3-25-5-7-27-9-11-29-13-15-31-17-19-33-21-22-34-20-18-32-16-14-30-12-10-28-8-6-26-4-2-24/h23-24H,1-22H2

InChIKey

PSVXZQVXSXSQRO-UHFFFAOYSA-N

SMILES

C(O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

EPA Substance Registry System

Undecaethylene glycol (6809-70-7)

3,6,9,12,15,18,21,24,27,30-decaoxadotriacontane-1,32-diol Usage And Synthesis

Description

PEG12 is a PEG chain consisting of 12 ethylene glycol subunits and two terminal hydroxyl groups. The hydroxyl groups can participate in reactions to further derivatize the compound. The hydrophilic PEG chain increases the water solubility of the compound in aqueous media. The water solubility properties of the PEG linker are enhanced with longer PEG chains.

Characteristics

PEG11-OH is a PEG derivative consisting of an undecaethylene glycol chain terminated by hydroxyl groups on both ends. It is a water-soluble compound.

Uses

HO-PEG11-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Application

PEG11-OH is widely used in various applications including pharmaceuticals, cosmetics, and materials science.

Definition

ChEBI: Undecaethylene glycol is a poly(ethylene glycol).

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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