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6,7-Dihydro-5H-quinolin-8-one

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6,7-Dihydro-5H-quinolin-8-one Basic information

Product Name:
6,7-Dihydro-5H-quinolin-8-one
Synonyms:
  • AKOS BB-8709
  • 6,7-DIHYDRO-5H-QUINOLIN-8-ONE
  • 6,7-DIHYDRO-5H-QUINOLINE-8-ONE
  • 6,7-DIHYDROQUINOLIN-8(5H)-ONE
  • 6,7-DIHYDRO-5H-QUINOLIN-8-ONE,99+%
  • 6,7-dihydro-5H-quinolin-8-one98%+,
  • 5,6,7,8-tetrahydroquinolin-8-one
  • 8(5H)-Quinolinone, 6,7-dihydro-
CAS:
56826-69-8
MF:
C9H9NO
MW:
147.17
EINECS:
225-682-9
Product Categories:
  • Quinoline Derivertives
  • Heterocycles
  • Heterocyclic Compound
Mol File:
56826-69-8.mol
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6,7-Dihydro-5H-quinolin-8-one Chemical Properties

Melting point:
96-98 °C(Solv: isopropyl ether (108-20-3))
Boiling point:
140 °C(Press: 0.1 Torr)
Density 
1.168±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
form 
A crystalline solid
pka
3.46±0.20(Predicted)
CAS DataBase Reference
56826-69-8(CAS DataBase Reference)
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Safety Information

HS Code 
2933499090
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6,7-Dihydro-5H-quinolin-8-one Usage And Synthesis

Description

6,7-Dihydro-5H-quinolin-8-one is a synthetic intermediate. It has been used in the synthesis of tetrahydropyridoazepinones and thiosemicarbazones with anticancer activity.

Chemical Properties

light yellow crystalline

Synthesis Reference(s)

The Journal of Organic Chemistry, 49, p. 2208, 1984 DOI: 10.1021/jo00186a027
Synthetic Communications, 33, p. 3497, 2003 DOI: 10.1081/SCC-120024729

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