Basic information Description Safety Supplier Related
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5'-DEOXYADENOSINE

Basic information Description Safety Supplier Related

5'-DEOXYADENOSINE Basic information

Product Name:
5'-DEOXYADENOSINE
Synonyms:
  • 5’-deoxy-adenosin
  • (2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-methyl-oxolane-3,4-diol
  • 6-Amino-9-(5-deoxy-β-D-ribofuranosyl)-9H-purine
  • 9-(5-Deoxy-β-D-ribofuranosyl)-9H-purine-6-amine
  • 5'-DEOXYADENOSINE
  • Adenosine, 5'-deoxy-
  • 5′-dAdo
  • 2'-Deoxycytidine Monohydrate(2'-dC ? H?O)
CAS:
4754-39-6
MF:
C10H13N5O3
MW:
251.24
Product Categories:
  • Biochemicals and Reagents
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides
Mol File:
4754-39-6.mol
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5'-DEOXYADENOSINE Chemical Properties

Melting point:
210-212 °C
Boiling point:
595.0±60.0 °C(Predicted)
Density 
1.93±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml; DMSO: 15 mg/ml
form 
A crystalline solid
pka
13.29±0.70(Predicted)
InChIKey
XGYIMTFOTBMPFP-KQYNXXCUSA-N
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Safety Information

WGK Germany 
3
RTECS 
AU7358650

MSDS

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5'-DEOXYADENOSINE Usage And Synthesis

Description

5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material, which has long been of interest in understanding the mechanism of aging, neurodegenerative diseases, and carcinogenesis. 

Uses

5′-Deoxyadenosine has been used:

  • as a standard in mass spectroscopy
  • as an inhibitor for screening thymidine phosphorylase activity
  • as a substrate in 5′-Deoxyadenosine deaminase (DadD) assay

Definition

ChEBI: A 5'-deoxyribonucleoside compound having adenosine as the nucleobase.

Biochem/physiol Actions

5′-Deoxyadenosine is a substrate for the enzyme methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase in microbes. 5′-Deoxyadenosine is a byproduct of cleavage of S-adenosylmethionine (SAM). High levels of 5′-Deoxyadenosine inhibits SAM dependent enzymes. It also inhibits biotin synthase (BioB) and lipoyl synthase (LipA) enzymes.

5'-DEOXYADENOSINESupplier

Fuyang Ziyi Biological Pharmaceutical Co., Ltd. Gold
Tel
19308655899
Email
2677609105@qq.com
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Email
info@sagechem.com
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Zouping Mingxing Chemical Co.,Ltd.
Tel
86-13605431940 13605431940
Email
zpmxchemical@126.com
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Email
hbeixys2001@163.com