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2',3'-Dideoxyuridine

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2',3'-Dideoxyuridine Basic information

Product Name:
2',3'-Dideoxyuridine
Synonyms:
  • BETA-D-2',3'-DIDEOXYURIDINE
  • DDU
  • 1-(2',3'-DIDEOXY-BETA-RIBOFURANOSYL)URACIL
  • 2',3'-DIDEOXYURIDINE
  • 1-[(2S,5R)-5-(hydroxyMethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyriMidine-2,4-dione
  • 2',3'-Dideoxy-D-uridine
  • 2'', 3''-DIDEOXYURIDINE (DDU)
  • 2',3'-ddU
CAS:
5983-09-5
MF:
C9H12N2O4
MW:
212.2
EINECS:
2017-001-1
Product Categories:
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Nucleosides-Dideoxy Nucleosides
Mol File:
5983-09-5.mol
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2',3'-Dideoxyuridine Chemical Properties

Melting point:
127-129 °C(lit.)
alpha 
34 º (C=0.4 IN H2O)
Density 
1.397±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: Slightly soluble; PBS (pH 7.2): 5 mg/ml
form 
A solid
pka
9.39±0.10(Predicted)
color 
White to off-white
optical activity
[α]20/D +34°, c = 0.4 in H2O
BRN 
750592
CAS DataBase Reference
5983-09-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
C
Risk Statements 
34-36/37
Safety Statements 
22-24/25-45-36/37/39-27-26
WGK Germany 
3
10-23
HS Code 
29349990

MSDS

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2',3'-Dideoxyuridine Usage And Synthesis

Chemical Properties

powder

Uses

2’,3’-Dideoxyuridine can be used as prodrug precursors or in antisense oligonucleotide synthesis. Also, it can be used to synthesize ProTide derivatives and evaluated against HIV-1 and HIV-2.

Uses

Research tool for antiviral and anticancer studies.

Definition

ChEBI: 2,3-dideoxyuridine is a pyrimidine 2',3'-dideoxyribonucleoside.

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