SeMilicoisoflavone B Chemical Properties

Boiling point:

615.5±55.0 °C(Predicted)

Density 

1.443±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Soluble in DMSO

pka

6.43±0.20(Predicted)

form 

Solid

color 

Light yellow to green yellow

biological source

plant

Water Solubility 

water: slightly soluble

Major Application

metabolomics
vitamins, nutraceuticals, and natural products

InChI

1S/C20H16O6/c1-20(2)4-3-10-5-11(6-15(23)19(10)26-20)13-9-25-16-8-12(21)7-14(22)17(16)18(13)24/h3-9,21-23H,1-2H3

InChIKey

LWZACZCRAUQSLH-UHFFFAOYSA-N

SMILES

[o]1c2c([c](c(c1)c3cc4c(c(c3)O)OC(C=C4)(C)C)=O)c(cc(c2)O)O

Safety Information

WGK Germany 

WGK 3

Storage Class

11 - Combustible Solids

SeMilicoisoflavone B Usage And Synthesis

Uses

It is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Definition

ChEBI: A member of the class of 7-hydroxyisoflavones that is 2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one substituted by hydroxy groups at positions 5, 7 and 8'. It has been isolated from Glycyrrhiza uralensis.

Biological Activity

Semilicoisoflavone B:

• Suppresses proinflammatory cytokine production, downregulates TLR4 expression, and diminishes reactive oxygen species generation in vitro.
• Inhibits the growth and division of cancer cells by triggering apoptosis and arresting the cell cycle, offering potential for effective tumor therapy.
• Restricts Caco-2 cell proliferation, suggesting potential for metabolic syndrome therapy.

SeMilicoisoflavone B(129280-33-7)Related Product Information

• Licoflaven B
• Glycyrrhizic acid
• Licochalcone B
• LICOCHALCONEC
• neoliquiritin
• 2-Propen-1-one,1-[4-[(2-O-D-apio-b-D-furanosyl-b-D-glucopyranosyl)oxy]-2-hydroxyphenyl]-3-(4-hydroxyphenyl)-, (2E)-
• Liquiritigenin-7-O-apiosyl(1-2)-glucoside
• Glycyroside
• 5,7-Dihydroxy-3-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-4H-1-benzopyran-4-one
• neoglycyrol
• Liquiritin apioside
• LICOFLAVONOL
• LICOISOFLAVONE A
• 4H-1-Benzopyran-4-one, 2-(4-(beta-D-glucopyranosyloxy)phenyl)-2,3-dihy dro-5,7-dihydroxy-, (2S)-
• Licorice glycoside C2
• ISOLIQUIRITIN
• 4,4'-DIHYDROXY-2-METHOXYCHALCONE
• isoliquiritin apioside