ISOLIQUIRITIN Chemical Properties

Melting point:

185-186℃

Boiling point:

743.5±60.0 °C(Predicted)

Density 

1.528

storage temp. 

4°C, protect from light

solubility 

Soluble in methan

form 

powder

pka

7.46±0.35(Predicted)

color 

Ochre

biological source

plant

ISOLIQUIRITIN Usage And Synthesis

Uses

It is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Definition

ChEBI: A monosaccharide derivative that is trans-chalcone substituted by hydroxy groups at positions 2' and 4' and a beta-D-glucopyranosyloxy group at position 4 respectively.

Biological Activity

Isoliquiritin triggers apoptotic cell death by increasing the levels of p53 and p21 in A549 non-small cell lung cancer cells while also inhibiting the p53-dependent pathway and revealing interactions with Akt activities. Futher, Isoliquiritin has demonstrated neuroprotective activity against oxidative stress and has the capability to restrain the growth of microbial pathogens.

target

HIV

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