LIQUIRITIN(SH) Chemical Properties

Melting point:

208 °C(Solv: ethanol (64-17-5))

Boiling point:

746.8±60.0 °C(Predicted)

Density 

1.529±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,2-8°C

solubility 

DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)

form 

Solid

pka

7.70±0.40(Predicted)

color 

White to Off-White

biological source

Glycyrrhizae root (licorice root)

Stability:

Light Sensitive

InChIKey

DEMKZLAVQYISIA-ZRWXNEIDSA-N

SMILES

O=C1C[C@@H](C2C=CC(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)=CC=2)OC2=CC(O)=CC=C12 |&1:3,9,10,11,13,15,r|

Safety Information

WGK Germany 

3

HS Code 

29389090

LIQUIRITIN(SH) Usage And Synthesis

Chemical Properties

White crystals, easily soluble in methanol, almost insoluble in ether, derived from licorice.

Uses

Liquiritin is a major constituent of Glycyrrhiza Radix that has a neuroprotective effect against glutamate toxicity in DPC12 cells and may have potential for the treatment of neurodegenerative diseases.

Definition

ChEBI: A flavanone glycoside that is liquiritigenin attached to a beta-D-glucopyranosyl residue at position 4' via a glycosidic linkage.

Biological Activity

Liquiritin has been attributed to show antidepressant-like and antioxidant activity. It causes apoptosis in cell lines having gastric cancer and promyelocytic leukemia. Liquiritin also demonstrates neurotrophic effects and hence has been considered as a potential contender for the management of different neurodegenerative diseases. It shows an anti-inflammatory property with protection to the liver against oxidative damage. It has depigmenting ability and is a potential medicine for melasma.

LIQUIRITIN(SH)(551-15-5)Related Product Information

• LICOCHALCONEC
• Fucoidan
• GlycyrrhizicFlavone
• Shikonin
• Glycyrrhizic acid ammonium salt
• Glycyrrhizic acid
• Glabridin
• Liguiritigenin-7-O-D-apiosyl-4’-O-D-glucoside
• Isoliquiritigenin
• LICOCHALCONE-A
• LIQUIRITIGENIN
• ISOLIQUIRITIN
• isoliquiritin apioside
• LIQUIRITIN(SH)
• Licochalcone B
• 4-[4-(beta-D-Glucopyranosyloxy)phenyl]-2-butanone
• 4'-METHOXYFLAVANONE
• Gastrodin