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LICOCHALCONEC

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LICOCHALCONEC Basic information

Product Name:
LICOCHALCONEC
Synonyms:
  • LICOCHALCONEC
  • 4,4'-Dihydroxy-2-Methoxy-3-prenylchalcone
  • 2-Propen-1-one,3-[4-hydroxy-2-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-1-(4-hydroxyphenyl)-,(2E)-
  • (E)-3-[4-hydroxy-2-methoxy-3-(3-methylbut-2-enyl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
  • Licoricchalcone C
  • (E)-3-(4-Hydroxy-2-methoxy-3-(3-methylbut-2-en-1-yl)phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
  • Licochalcone C, 10 mM in DMSO
CAS:
144506-14-9
MF:
C21H22O4
MW:
338.4
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Chalcones
  • sy
Mol File:
144506-14-9.mol
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LICOCHALCONEC Chemical Properties

Boiling point:
536.1±50.0 °C(Predicted)
Density 
1.181±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
-20°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
powder
pka
7.82±0.15(Predicted)
color 
Yellow
biological source
plant
Major Application
metabolomics
vitamins, nutraceuticals, and natural products
InChI
1S/C21H22O4/c1-14(2)4-11-18-20(24)13-8-16(21(18)25-3)7-12-19(23)15-5-9-17(22)10-6-15/h4-10,12-13,22,24H,11H2,1-3H3/b12-7+
InChIKey
WBDNTJSRHDSPSR-KPKJPENVSA-N
SMILES
O(C)c1c(c(ccc1\C=C\C(=O)c2ccc(cc2)O)O)CC=C(C)C
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Safety Information

WGK Germany 
WGK 3
Storage Class
11 - Combustible Solids
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LICOCHALCONEC Usage And Synthesis

Chemical Properties

Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the rhizome of licorice.

Uses

It is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biological Activity

According to the existing research, Licochalcone C may have an effect on processes related to inflammation and cell death regulation by inhibiting the expression of TNF-α, Caspase and Bcl-2/Bax

target

TNF-α | Caspase | Bcl-2/Bax

LICOCHALCONECSupplier

Shenzhen Sungening Bio-Tech Co., Ltd
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+86-0755-89668383
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sales@sungening.com
Chengdu Ai Keda Chemical Technology Co., Ltd.
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4008-755-333 18080918076
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800078821@qq.com
Chengdu Climax Biotech Co., Ltd.
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028-83311324 1278112614
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climaxbiotech@gmail.com
Beijing HuaMeiHuLiBiological Chemical
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010-56205725
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waley188@sohu.com
Shanghai Ruji Biology Technology Co., Ltd.
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+86-21-65211385-8001 36031160
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sales@shruji.com