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ISORHYNCHOPHYLLINE

Basic information Safety Supplier Related

ISORHYNCHOPHYLLINE Basic information

Product Name:
ISORHYNCHOPHYLLINE
Synonyms:
  • ISORHYNCHOPHYLLINE
  • (16E,20α)-16,17-Didehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester
  • (7S,16E,20R)-16,17-Didehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester
  • 7-Isorhynchophylline
  • 7-Isorhyncophylline
  • ISORHYNCHOPHYLLINE (RG)
  • SUCROSE(USP)(RG)
  • ISORHYNCHOPHYLLINE (P)
CAS:
6859-01-4
MF:
C22H28N2O4
MW:
384.47
Mol File:
6859-01-4.mol
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ISORHYNCHOPHYLLINE Chemical Properties

Melting point:
114℃
Boiling point:
560.8±50.0 °C(Predicted)
Density 
1.23
solubility 
DMSO : 100 mg/mL (260.10 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form 
powder
pka
13.61±0.60(Predicted)
color 
White
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Safety Information

Safety Statements 
24/25
HS Code 
29389090
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ISORHYNCHOPHYLLINE Usage And Synthesis

Description

This amorphous base has been isolated from Ourouparia rhyncophylla Mats. It has [α]29Db + 8.3° and yields a crystalline perchlorate, m.p. 150°C (dec.).

Uses

Isorhynchophylline is an oxindole alkaloid which has been the main active ingredient of Uncaria rhynchophylla contributing to anti-depressant like behavior in subjects.

Definition

ChEBI: A natural product found in Uncaria macrophylla.

target

Potassium Channel

References

Kondo, Fukuda, Tomita., J. Pharm. Soc., Japan, 48, 54 (1928) Kondo, Ikeda., ibid, 57,237 (1937)

ISORHYNCHOPHYLLINESupplier

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