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ChemicalBook >  Product Catalog >  Analytical Chemistry >  Standard >  Pharmaceutical Impurity Reference Standards >  (3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

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(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Basic information

Product Name:
(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
Synonyms:
  • (3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
  • (3S,4R,3'S)-Ezetimibe
  • zetimibe (3S,4R,3'S)-Isomer
  • Ezetimibe Impurity E
  • Ezetimibe impuriry 20/ (3’S)-ent-Ezetimibe/(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
  • Ezetimibe-19
  • Ezetimibe (SSR)-Isomer
  • Ezetimibe impurities 17
CAS:
1593543-00-0
MF:
C24H21F2NO3
MW:
409.43
Mol File:
1593543-00-0.mol
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(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Chemical Properties

Boiling point:
654.9±55.0 °C(Predicted)
Density 
1.334±0.06 g/cm3(Predicted)
solubility 
Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
pka
9.72±0.30(Predicted)
color 
White
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(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Usage And Synthesis

Uses

An enantiomeric impurity of Ezetimibe (E975005), an antihyperlipoproteinemic and cholesterol absorption inhibitor.

(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-oneSupplier

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