8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Basic information
- Product Name:
- 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- Synonyms:
-
- 8-(4-chlorophenylthio)guanosine*3’:5’-cyclicmono
- 8-(4-chlorophenylthio)guanosine-3’,5’-cyclicmonophosphate(8-pcpt-cgmp),sodiumsalt
- 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3':5'-CYLIC MONOPHOSPHATE SODIUM SALT
- 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- 8-PCPT-CGMP NA
- 8-PCPT-CGMP SODIUM SALT
- 8-PCPT-CGMP TEA
- CGMP, 8-PCPT-, NA
- CAS:
- 51239-26-0
- MF:
- C16H14ClN5NaO7PS
- MW:
- 509.79
- Mol File:
- 51239-26-0.mol
8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Chemical Properties
- storage temp.
- -20°C
- solubility
- H2O: 25 mg/mL
- form
- powder
- color
- white
MSDS
- Language:English Provider:SigmaAldrich
8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Usage And Synthesis
Uses
8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt has been used to activate GMP-dependent protein kinase (PKG) in vascular smooth muscle cells (VSMCs).
Definition
ChEBI: 8-(4-chlorophenylthio)-cGMP.Na is an organic sodium salt that is the monosodium salt of 8-(4-chlorophenylthio)-cGMP. It has a role as a protein kinase agonist. It contains an 8-(4-chlorophenylthio)-cGMP(1-).
Biochem/physiol Actions
Membrane-permeable analog of cGMP that does not affect cGMP-regulated phosphodiesterase. A more potent cGMP analog than 8-Br-cGMP due to greater membrane permeability and a higher resistance to hydrolysis by phosphodiesterase. Used as a selective activator of cGMP dependent protein kinase (PKG). Found to be a very potent cyclic nucleotide-gated channel agonist.
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8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT(51239-26-0)Related Product Information
- POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT
- 8-PCPT-CGMP, TEA
- NADA
- ANISOMYCIN
- 8(S)-HETE
- 5-AMINO-1-METHYL-2-(METHYLTHIO)-1H-IMIDAZOLE-4-CARBOXAMIDE
- GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- 8-MERCAPTOGUANOSINE
- 5-AMINO-2-MERCAPTO-1-METHYL-1H-IMIDAZOLE-4-CARBOXAMIDE
- guanine hydrochloride
- 9-((2-hydroxy-1,3,2-dioxaphosphorinan-5-yl)oxymethyl)guanine P-oxide
- 2'-DCGMP SODIUM SALT
- 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- INOSINE-3',5'-CYCLIC PHOSPHATE