1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane Chemical Properties

form 

Liquid

color 

Colorless to light yellow

1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane Usage And Synthesis

Biological Activity

Bromo-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane(1056969-61-9)Related Product Information

• BocNH-PEG7-CH2CH2N3
• Azido-PEG7-NHS ester
• Azide-PEG7-Tos
• Amino-PEG8-azide
• Azido-PEG8-acid
• Azido-PEG7-hydrazide
• Azido-PEG7-azide
• Azido-PEG7-COOtBu
• N3-PEG7-OH