2,4-Dihydroxybenzophenone Chemical Properties

Melting point:

144.5-147 °C(lit.)

Boiling point:

194 °C (1 mmHg)

Density 

1,32 g/cm³

vapor pressure 

0Pa at 25℃

refractive index 

1.5090 (estimate)

Flash point:

125 °C

storage temp. 

Store below +30°C.

solubility 

Chloroform (Slightly, Heated), Ethanol (Slightly, Heated)

pka

7.72±0.35(Predicted)

form 

Crystalline Powder

color 

Yellow

PH

5 (10g/l, H2O, 20℃)(slurry)

Water Solubility 

insoluble

Merck 

14,1106

BRN 

1311566

InChIKey

ZXDDPOHVAMWLBH-UHFFFAOYSA-N

LogP

2.964 at 25℃

CAS DataBase Reference

131-56-6(CAS DataBase Reference)

NIST Chemistry Reference

Methanone, (2,4-dihydroxyphenyl)phenyl-(131-56-6)

EPA Substance Registry System

Methanone, (2,4-dihydroxyphenyl)phenyl- (131-56-6)

Safety Information

Hazard Codes 

Xi,T

Risk Statements 

36-36/37/38-61

Safety Statements 

26-37/39-45-53

WGK Germany 

2

RTECS 

DJ0700000

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29145000

Hazardous Substances Data

131-56-6(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: > 5000 mg/kg

MSDS

• Language:English Provider:(2,4-dihydroxyphenyl)phenyl-methanone
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2,4-Dihydroxybenzophenone Usage And Synthesis

Chemical Properties

yellow crystalline powder

Uses

Novel mordent and disperse azo dyes were prepared by the coupling of various diazo solutions of aromatic amines with 2, 4-dihydroxybenzophenone. The ultraviolet absorbing monomers were synthesized by reaction of 2, 4-dihydroxybenzophenone with glycidyl acrylate and glycidyl methacrylate. Two new polymerizable stabilizers, 4-benzoyl-2-(α-piperidino-2-chlorobenzyl)-3-hydroxyphenyl acrylate (BPBHA) and corresponding methacrylate (BPBHMA), were synthesized and characterized from 2,4-Dihydroxybenzophenone. a polymerizable UV-stabilizer, 2-hydroxy-4-(3-methacryloxy-2-hydroxylpropoxy) benzophenone (BPMA), was synthesized using 2, 4-dihydroxybenzophenone (UV-0) and glycidyl methacrylate (GMA).

Uses

2,4-Dihydroxybenzophenone is an metabolite of Benzophenone (B204980), an compound used in the manufacturing of antihistamines, hypnotics and insecticides.

Uses

Ultraviolet light absorber, especially in paints and plastics.

Definition

ChEBI: 2,4-Dihydroxybenzophenone is a member of benzophenones.

Preparation

Obtained by condensation of benzanilide with resorcinol in the presence of zinc chloride and phosphorous oxychloride at 130–140° for 1 h (25%).

Contact allergens

BZP-1 is used, for example, in paints, plastics, and nail varnishes.

Safety Profile

Poison by intravenous and intraperitoneal routes. Mildly toxic by ingestion. An eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

Recrystallise it from MeOH. [Beilstein 8 IV 2442.]

2,4-Dihydroxybenzophenone(131-56-6)Related Product Information

• Ethyl 4-[[(methylphenylamino)methylene]amino]benzoate
• Bis(4-fluorophenyl)-methanone
• 2-Phenylbenzimidazole-5-sulfonic acid
• UV Absorber 326
• (3,4-Diaminophenyl)phenylmethanone
• 4,4'-Dimethylbenzophenone
• UV-329
• 2,4-Difluorobenzophenone
• Benzophenone
• Diphenyl ether
• Octabenzone
• Benzophenone imine
• Oxybenzone
• Drometrizole
• PHENYL VALERATE
• Phenyl salicylate
• Acetaldehyde
• 2,2-Bis(hydroxymethyl)propionic acid