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DMT-2'O-Methyl-rU Phosphoramidite

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DMT-2'O-Methyl-rU Phosphoramidite Basic information

Product Name:
DMT-2'O-Methyl-rU Phosphoramidite
Synonyms:
  • 3-({[(2-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-5-(2,4-DIOXO-3H-PYRIMIDIN-1-YL)-4-METHOXYOXOLA
  • DMT-2'O-ME-RU AMIDITE 0.5G 89 SINGLE
  • 2'-O-methyluridine-ce phosphoramidite*for abi
  • DMT-2'O-Me-rU Amidite 10g, Single
  • DMT-2'O-ME-RU AMIDITE 0.5G AB SINGLE
  • 2’-O-Methy-rUPhosphoramidite
  • N-blocked-5'-O-DMT-2'-O-Me CED uridine phosphoramidite
  • 5'-O-(4,4-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
CAS:
110764-79-9
MF:
C40H49N4O9P
MW:
760.82
EINECS:
200-100-5
Mol File:
110764-79-9.mol
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DMT-2'O-Methyl-rU Phosphoramidite Chemical Properties

storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO : 100 mg/mL (131.44 mM; Need ultrasonic)
form 
powder
pka
9.39±0.10(Predicted)
color 
white to off-white
InChI
InChI=1/C40H49N4O9P/c1-27(2)44(28(3)4)54(51-25-11-23-41)53-36-34(52-38(37(36)49-7)43-24-22-35(45)42-39(43)46)26-50-40(29-12-9-8-10-13-29,30-14-18-32(47-5)19-15-30)31-16-20-33(48-6)21-17-31/h8-10,12-22,24,27-28,34,36-38H,11,25-26H2,1-7H3,(H,42,45,46)/t34-,36-,37-,38-,54?/s3
InChIKey
UVUOJOLPNDCIHL-XKZJCBTISA-N
SMILES
C(C1C=CC=CC=1)(C1C=CC(OC)=CC=1)(C1C=CC(OC)=CC=1)OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OC)[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C |&1:25,27,36,39,r|
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Safety Information

WGK Germany 
3
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DMT-2'O-Methyl-rU Phosphoramidite Usage And Synthesis

Uses

DMT-2'O-Methyl-rU Phosphoramidite is a white to off-white powder and is used as a pharmaceutical intermediate for pharmaceutical synthesis and scientific research.

Application

2′O-Methyl RNA nucleoside including DMT-2′O-Methyl-rU Phosphoramidite can be advantageously incorporated in nucleic acid probes with RNA or DNA for in-vivo or in-vitro applications to convey nuclease resistance.The unique combination of properties of 2′O-Methyl RNA had found widespread use in the fields of:
Diagnostic probes
Aptamer and ribozyme development
Mixed 2′O-Methyl-RNA/DNA antisense molecules

DMT-2'O-Methyl-rU PhosphoramiditeSupplier

Wuhu Huaren Science and Technology Co., Ltd. Gold
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0553-0553-0553-5842013-801-801 18155347026
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Wuhu Nuowei Chemical Technology Co., Ltd Gold
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0553-8233716 18055326116
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kendoll@cqpharm.com
Hefei Huana Biomedical Technology Co.,Ltd Gold
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17333066501
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shengwen.fang@huanaok.com.cn
Hefei Stongbio Co.,Ltd. Gold
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13326014885
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service@nugene.com.cn