Methyl (R)-(+)-lactate Chemical Properties

Boiling point:

144-145 °C(lit.)

alpha 

8.5 º (c=neat)

Density 

1.09 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.413(lit.)

Flash point:

121 °F

storage temp. 

Inert atmosphere,2-8°C

solubility 

Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly)

pka

13.07±0.20(Predicted)

form 

Liquid

color 

Clear colorless

optical activity

[α]21/D +8.4°, neat

Water Solubility 

miscible, hydrolyses

Merck 

14,6094

InChIKey

LPEKGGXMPWTOCB-GSVOUGTGSA-N

LogP

-0.719 (est)

CAS DataBase Reference

17392-83-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

10-36/37

Safety Statements 

16-24-24/25

RIDADR 

UN 3272 3/PG 3

WGK Germany 

1

HazardClass 

3

PackingGroup 

III

HS Code 

29181100

MSDS

• Language:English Provider:Methyl (R)-(+)-lactate
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

Methyl (R)-(+)-lactate Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

(+)-Methyl D-lactate can be used as a starting material in the asymmetric preparation of:

• Neomethymycin, a macrolide which contains 12-membered macrolactone that is used as a potent biological agent.
• PM-toxin A.

It can also be used as a chiral pool along with D-(-)-tartaric acid in the stereoselective total synthesis of separacenes A and B via Trost-Rychnovsky alkyne rearrangement, Horner-Wadsworth-Emmons olefination as well as Corey-Bakshi-Shibata reaction.

Definition

ChEBI: A methyl lactate that has R configuration.

General Description

This compound has benign qualities and is biodegradable, water miscible, and functions as a versatile solvent for CA membrane preparation. This is also used as an intermediate for the production of other chemicals, polymers, and derivatives. Thus this product has been enhanced for Safer solvents and auxiliaries.

Methyl (R)-(+)-lactate(17392-83-5)Related Product Information

• Methyl pentafluoropropionate
• 4-Methoxyphenol
• Methyl salicylate
• Methyl propionate
• Methylparaben
• Benyl propionic methyl ester
• Methyl 2-bromopropionate
• Hydroxyapatite
• Hydroxy silicone oil
• Bensulfuron methyl
• Calcium lactate
• Methyl formate
• Methyl levulinate
• 10-Hydroxycamptothecin
• Methyl 2-chloropropionate
• Methyl 3-bromopropionate
• Thiophanate-methyl
• Potassium lactate