Basic information Safety Supplier Related

2'-Chloro-4'-hydroxyacetophenone

Basic information Safety Supplier Related

2'-Chloro-4'-hydroxyacetophenone Basic information

Product Name:
2'-Chloro-4'-hydroxyacetophenone
Synonyms:
  • 1-(4-HYDROXY-2-CHLOROPHENYL)ETHANONE
  • 1-(2-CHLORO-4-HYDROXY-PHENYL)-ETHANONE
  • 2'-CHLORO-4'-HYDROXYACETOPHENONE
  • 4'-HYDROXY-2'-CHLORO ACETOPHENONE
  • 4-HYDROXY-2-CHLOROACETOPHENONE
  • 1-(2-Chloro-4-hydroxyphenyl)ethan-1-one
  • 1-(2-Chloro-4-hydroxyphenyl)ethan-1-one, 4-Acetyl-3-chlorophenol
  • MELU-001
CAS:
68301-59-7
MF:
C8H7ClO2
MW:
170.59
Mol File:
68301-59-7.mol
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2'-Chloro-4'-hydroxyacetophenone Chemical Properties

Melting point:
110 °C
Boiling point:
288.0±20.0 °C(Predicted)
Density 
1.298±0.06 g/cm3(Predicted)
pka
7.21±0.18(Predicted)
form 
claggy powder
color 
Dirty cream (hint of peach)
CAS DataBase Reference
68301-59-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Hazard Note 
Irritant
HS Code 
2914500090
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2'-Chloro-4'-hydroxyacetophenone Usage And Synthesis

Uses

1-(2-Chloro-4-hydroxyphenyl)ethanone is used in preparation of aminopyrazine compounds as HPK1 inhibitor and the use thereofof aminopyrazine compounds as HPK1 inhibitor and the use thereof.

Preparation

Obtained (by-product) by Fries rearrangement of 3-chlorophenyl acetate with aluminium chloride.

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