3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Chemical Properties

Boiling point:

266∶C

Density 

1.72

Flash point:

115∶C

storage temp. 

2-8°C(protect from light)

form 

solid

pka

6.27±0.20(Predicted)

color 

Yellow

CAS DataBase Reference

486460-21-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

HS Code 

2933998090

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Usage And Synthesis

Uses

3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine is primarily used as an important intermediate in organic synthesis. The introduction of the trifluoromethyl group imparts excellent chemical and thermal stability to this compound, allowing it to react under relatively harsh conditions. Furthermore, it possesses certain biological and pharmacological activities, making it a potential candidate compound for drug development. Therefore, it has wide applications in organic synthesis, materials science, and drug development.

Chemical Properties

White crystalline powder

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine(486460-21-3)Related Product Information

• Tetramethylpyrazine
• Terazosin
• Prazosin
• Levomepromazine hydrochloride
• Pyrazine
• Terazosin hydrochloride
• Doxazosin
• Sitagliptin
• Sitagliptin phosphate monohydrate
• Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate
• Sitagliptin S-IsoMer
• 3-(tert-butoxycarbonyl aMino)-4-(2,4,5-trifluoro phenyl)butanoic acid
• 1-(2,4,5-trifluorophenyl)propan-2-one
• (S)-1-(2,4,5-trifluorophenyl)propan-2-amine hydrochloride
• Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate
• tert-butyl 4-oxo-4-(3-(trifluoroMethyl)-5,6-dihydro-[1,2,4]triazolo [4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl) butan-2-ylcarbaMate
• (S)-methyl 3-amino-4-(2,4,5-trifluoro phenyl) butanoate
• 1-(2,4,5-trifluorophenyl)propan-2-amine hydrochloride