1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[13-(4-formylphenyl)-13-oxo-3,6,9-trioxa-12-azatridec-1-yl]hexahydro-2-oxo-, (3aS,4S,6aR)- Chemical Properties

Boiling point:

880.0±65.0 °C(Predicted)

Density 

1.219±0.06 g/cm3(Predicted)

pka

13.53±0.46(Predicted)

form 

Solid

color 

Off-white to light yellow

1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[13-(4-formylphenyl)-13-oxo-3,6,9-trioxa-12-azatridec-1-yl]hexahydro-2-oxo-, (3aS,4S,6aR)- Usage And Synthesis

Uses

Biotin-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[13-(4-formylphenyl)-13-oxo-3,6,9-trioxa-12-azatridec-1-yl]hexahydro-2-oxo-, (3aS,4S,6aR)-(889443-90-7)Related Product Information

• EZ-LINK (TM) PFP-BIOTIN, 50 MG
• Biotin-PEG7-Amine
• Biotin-PEG2-NH-Boc
• Biotin-PEG2-Hydrazide
• 15-[D(+)-BIOTINYLAMINO]-4,7,10,13-TETRAOXAPENTADECANOIC ACID
• 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-[2-(2-hydroxyethoxy)ethyl]-2-oxo-, (3aS,4S,6aR)-
• Biotin-PEG5-azide
• Biotin-peg3-alcohol
• Biotin-PEG3-Me-Tet
• Biotin-PEG3-t-butyl ester
• 21-[D(+)-Biotinylamino]-4,7,10,13,16,19-hexaoxaheneicosanoic acid
• 4,7,10,13-Tetraoxa-16-azaheneicosanoic acid, 21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-, 1,1-dimethylethyl ester
• Biotin-PEG3-N3
• (+)-Biotin-PEG6-NHS Ester
• Biotin-PEG4-Silane
• Biotin-PEG4-PFP ester
• Biotin-PEG3-oxyamine
• Biotin-PEG5-NH-Boc