Ethyl 4,6-dichloronicotinate
Ethyl 4,6-dichloronicotinate Basic information
- Product Name:
- Ethyl 4,6-dichloronicotinate
- Synonyms:
-
- 4,6-Dichloronicotinic acid ethyl ester ,97%
- ethyl 4,6-dichloronicotinate (en)
- Ethyl 4,6-dichloronicotinate ,97%
- ethyl 4,6-dichloropyridine-3-carboxylate
- 3-Pyridinecarboxylicacid,4,6-dichloro-,ethylester
- 4,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER
- 4,6-DICHLORONICOTINIC ACID ETHYL ESTER
- ETHYL 4,6-DICHLORONICOTINATE
- CAS:
- 40296-46-6
- MF:
- C8H7Cl2NO2
- MW:
- 220.05
- Product Categories:
-
- Pyridine series
- Boronic Acid
- Mol File:
- 40296-46-6.mol
Ethyl 4,6-dichloronicotinate Chemical Properties
- Melting point:
- 32-34°
- Boiling point:
- 85°C/0.01mmHg(lit.)
- Density
- 1.367±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Soluble in methanol.
- pka
- -1.24±0.10(Predicted)
- form
- Liquid
- color
- Yellow
- InChI
- InChI=1S/C8H7Cl2NO2/c1-2-13-8(12)5-4-11-7(10)3-6(5)9/h3-4H,2H2,1H3
- InChIKey
- AAUBVINEXCCXOK-UHFFFAOYSA-N
- SMILES
- C1=NC(Cl)=CC(Cl)=C1C(OCC)=O
Ethyl 4,6-dichloronicotinate Usage And Synthesis
Uses
Ethyl 4,6-Dichloronicotinate acts as a reactant in the preparation of (acylamino)aminonaphthyridinones as novobiocin analogs and Hsp90 inhibitors, their antitumor activities in human breast cancer cell lines, and the effects on aptoptosis and cell cycle advancement of selected compounds.
Chemical Properties
White solid
Uses
Ethyl 4,6-dichloronicotinate is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals, and dyestuffs. It is also used as a fine chemical intermediate. Ethyl-4,6-dichloronicotinate could be used as a starting material to synthesize 6-chlorothieno[3,2-c]pyridine-2-carbohydrazide-hydrazone subsidiaries[1].
References
[1] N. Rao, K. Prasad, M. Rao. “Synthesis and Antibacterial Evaluation of Hydrazone Derivatives Bearing 6-Chlorothieno[3,2-c]pyridine Moiety.” Asian Journal of Chemistry 1 1 (2019).
Ethyl 4,6-dichloronicotinate Preparation Products And Raw materials
Raw materials
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Ethyl 4,6-dichloronicotinate(40296-46-6)Related Product Information
- Ethyl acetoacetate
- 4,6-Dichloronicotinic acid
- 6-Chloronicotinic acid
- Ethyl pyruvate
- Ethyl acrylate
- Thionyl chloride
- Ethyl oleate
- Ethyl acetate
- Ethanol
- 2-Chloronicotinic acid
- Ethyl nicotinate
- 2,5-Dichloronicotinic acid
- 2,6-Dichloronicotinic acid
- Tris(trimethylsilyl)phosphate
- 5,6-Dichloronicotinic acid
- Ethyl formate
- Ethyl cyanoacetate
- Ethylparaben