Diethyl 1,3-acetonedicarboxylate Chemical Properties

Melting point:

125 °C

Boiling point:

250 °C (lit.)

Density 

1.113 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.440(lit.)

Flash point:

187 °F

storage temp. 

Sealed in dry,2-8°C

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

pka

9.66±0.46(Predicted)

form 

Liquid

color 

Clear colorless to pale yellow

Water Solubility 

10 g/L (20 ºC)

Sensitive 

Moisture Sensitive

BRN 

640146

InChIKey

ZSANYRMTSBBUCA-UHFFFAOYSA-N

CAS DataBase Reference

105-50-0(CAS DataBase Reference)

NIST Chemistry Reference

Pentanedioic acid, 3-oxo-, diethyl ester(105-50-0)

EPA Substance Registry System

Pentanedioic acid, 3-oxo-, diethyl ester (105-50-0)

Safety Information

Hazard Codes 

F,Xi

Risk Statements 

36/37/38

Safety Statements 

23-24/25-36-26

RIDADR 

UN 2810

WGK Germany 

3

Hazard Note 

Flammable/Moisture Sensitive

TSCA 

Yes

HS Code 

29183000

MSDS

• Language:English Provider:Diethyl 1,3-acetonedicarboxylate
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Diethyl 1,3-acetonedicarboxylate Usage And Synthesis

Chemical Properties

clear colorless to pale yellow liquid

Uses

Diethyl 1,3-acetonedicarboxylate was used in the synthesis of novel pyrido[4,3,2-de]quinoline, isoquinolino[6,5,4,3-cde] quinoline and pyrazomycin. It was used as starting reagent in the synthesis of (±)-thienamycin, potent β-lactam antibiotic.

Diethyl 1,3-acetonedicarboxylate(105-50-0)Related Product Information

• Diacetone Alcohol
• Glutaric acid
• Diethyl azodicarboxylate
• Dimethyl Glutarate
• 2-Ketoglutaric acid
• Ethyl 2,4-dioxovalerate
• Ethyl pyruvate
• Diethyl phosphite
• Phenoxyethyl isobutyrate
• Diethyl malonate
• 1,3-Acetonedicarboxylic acid
• Acetonylsuccinic acid diethyl ester
• Diethyl chloromalonate
• Diethyl oxalate
• Ethylene glycol diethyl ether
• Dimethyl 1,3-acetonedicarboxylate
• Mefenpyr-diethyl
• Diethyl phthalate