Chloramine-T trihydrate Chemical Properties

Melting point:

167-170 °C(lit.)

Density 

1.43

Flash point:

92 °C

storage temp. 

Store at +2°C to +8°C.

solubility 

H2O: passes test

form 

Crystalline Powder

pka

pK1:4.54(+1) (25°C)

color 

White to off-white

PH

8-10 (50g/l, H2O, 20℃)

Odor

Chlorine like

PH Range

8 - 10

Water Solubility 

Soluble in water and ethyl alcohol. Insoluble in benzene and ethers.

Sensitive 

Moisture Sensitive

Merck 

14,2075

BRN 

3924168

LogP

2.111 (est)

CAS DataBase Reference

7080-50-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

C

Risk Statements 

22-31-34-42

Safety Statements 

22-26-36/37/39-45-7

RIDADR 

UN 3263 8/PG 3

WGK Germany 

2

RTECS 

XT5616800

TSCA 

Yes

HazardClass 

8

PackingGroup 

III

HS Code 

29350090

Toxicity

LD50 orally in Rabbit: 935 mg/kg

MSDS

• Language:English Provider:ACROS
• Language:English Provider:ALFA

Chloramine-T trihydrate Usage And Synthesis

Chemical Properties

Chloramine T is a white to yellow crystalline powder with characteristic odor. It is an air sensitive and corrosive, cause eye and skin burns and chemical dangers: Chloramine T is known to explode on heating above 130°C (anhydrous). Chloramine T decomposes slowly under the influence of air producing chlorine (trihydrate). On heating or on contact with acids it decomposes and produce toxic gases.

Description

Chloramine-T is commercially available in the form of a trihydrate and is a stable white to pale yellow solid. Chloramine T Sodium Salt Trihydrate is a reagent for selective oxidation of methionine. It is used as an antibacterial agent; a topical antiseptic. Capable of oxidative cyclization to produce various heterocycles. Nitrene source for aziridinations and aminohydroxylations. Reactant for Preparation of factor Xa inhibitors as novel anticoagulants.

Uses

Chloramine-T trihydrate can be used for detection of bromate and halogens.

Uses

Detection of bromate and halogens. Source of halonium ions and nitrogen anions in organic synthesis.

Uses

Chloramine-T trihydrate is used as an intermediate in the manufacture of chemical substances such as pharmaceuticals. It combines with iodogen or lactoperoxidase and is commonly used for labeling peptides and proteins with radioiodine isotopes. Hypochlorite released from chloramine-T acts as an effective oxidizing agent for iodide to form iodine monochloride (ICl).

General Description

Chloramine T (CAT) trihydrate is a commonly used reagent for organic synthesis especially in heterocyclic chemistry. CAT is an active chlorine compound that shows antimicrobial activity.

Purification Methods

Recrystallise it from hot water (2mL/g). Dry it in a desiccator over CaCl2 where it loses water. Protect it from sunlight. It is used for the detection of bromate and halogens, and Co, Cr, Fe, Hg, Mn, Ni and Sb ions. [Campbell & Johnson Chem Rev 78 65 1978, Bremner Synthetic Reagents 6 9 1985, Chattaway J Chem Soc 87 145 I1905, Inglis J Soc Chem Ind (Lond) 37 288 1918, Beilstein 11 H 107, 11 I 29, 11 II 62, 11 III 300, 2 IV 457.]

Chloramine-T trihydrate(7080-50-4)Related Product Information

• Levofloxacin heMihydrate
• Tosylmethyl isocyanide
• Sodium chloride
• Benzenesulfonyl chloride
• Sodium gluconate
• Sodium xylenesulfonate
• Sodium carbonate
• Sodium acetate
• 4-Nitrobenzenesulfonyl chloride
• Tosyl chloride
• Sodium hydroxide
• Sodium bicarbonate
• p-Toluenesulfonamide
• Sulfuryl chloride
• p-Toluenesulfonic acid monohydrate
• Sodium benzoate
• 4-Methoxybenzenesulfonyl chloride
• Chloramine-T