cyclopentyl 2-cyclohexyl-2-((6-(3-(hydroxyamino)-3-oxopropyl)pyridin-3-yl)methylamino)acetate Chemical Properties

storage temp. 

Store at -20°C

solubility 

DMSO:81.0(Max Conc. mg/mL);200.73(Max Conc. mM)
Ethanol:15.0(Max Conc. mg/mL);37.17(Max Conc. mM)

form 

A crystalline solid

color 

Light yellow to khaki

cyclopentyl 2-cyclohexyl-2-((6-(3-(hydroxyamino)-3-oxopropyl)pyridin-3-yl)methylamino)acetate Usage And Synthesis

Description

GSK3117391 is a histone deacetylase (HDAC) inhibitor (IC₅₀ = <100 nM in HeLa nuclear extracts). It inhibits growth of U937 and HUT cancer cells (IC₅₀s = <330 nM).

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