ALPHA-APO-OXYTETRACYCLINE Chemical Properties

Melting point:

200°C

Boiling point:

742.4±60.0 °C(Predicted)

Density 

1.62±0.1 g/cm3(Predicted)

storage temp. 

Refrigerator, Under Inert Atmosphere

solubility 

Aqueous Base (Slightly), Methanol (Slightly)

pka

1.62±0.58(Predicted)

form 

Crystalline Powder

color 

Khaki

Stability:

Hygroscopic, Unstable in basic solution

EPA Substance Registry System

1-Cyclohexene-1-carboxamide, 4-(1,3-dihydro-4,5-dihydroxy-9-methyl-3-oxonaphtho[2,3-c]furan-1-yl)-3-(dimethylamino)-2,5-dihydroxy-6-oxo-, stereoisomer (18695-01-7)

Safety Information

HS Code 

29413020

MSDS

• Language:English Provider:ACROS

ALPHA-APO-OXYTETRACYCLINE Usage And Synthesis

Chemical Properties

khaki-coloured crystalline powder

Uses

Oxytetracycline metabolite (absolute stereochemistry unknown)

Uses

α-Apooxytetracycline is a degradation product of oxytetracycline, formed under acidic conditions. An initial dehydration to anhydrooxytetracycline then undergoes an internal cyclisation of the C5-OH to the C12 ketone. The resulting cleavage of the C12-C12a bond generates two isomers, α- and β-apooxytetracycline. α-apooxytetracycline is an important standard for monitoring oxytetracycline stability.

Uses

α-Apooxytetracycline is a degradation product of oxytetracycline, formed under acidic conditions. After initial dehydration to anhydrooxytetracycline, it undergoes an internal cyclisation of the C5-OH to the C12 ketone. The resulting cleavage of the C12-C12a bond generates two isomers, α- and β-apooxytetracycline. α-Apooxytetracycline is an important standard for monitoring oxytetracycline stability.

ALPHA-APO-OXYTETRACYCLINE(18695-01-7)Related Product Information

• ALPHA-APO-OXYTETRACYCLINE
• 2-acetyl-2-decarboxamidooxytetracycline
• 4-Epioxytetracycline
• Tetracycline
• (4S,4aR,5R,12aS)-4-(dimethylamino)-3,5,10,11,12a-pentahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide
• 2-METHYL-1-PHENYL-1-PENTANOL
• Hexyl salicylate
• ETHYL 2-NAPHTHOATE
• 2,3-DIMETHYLNAPHTHALENE
• METHYL 2-NAPHTHOATE
• Isobutyl salicylate
• 1-HYDROXY-3-CYCLOHEXENE
• 2-Naphthoic acid
• 2-Ethylhexyl salicylate
• SALICYLIC ACID N-PROPYL ESTER
• Amyl salicylate
• 1,2-DIMETHYLNAPHTHALENE
• Oxytetracycline